奥曲肽联合乌司他丁治疗急性胰腺炎效果观察  

Observation on the Effect of Octreotide Combined With Ulinastatin in the Treatment of Acute Pancreatitis

作　　者：夏秀梅[1] XIA Xiumei(Department of Gastroenterology, Xiaogan Central Hospital,Xiaogan Hubei 432000, China)

机构地区：[1]孝感市中心医院消化内科

出　　处：《中国继续医学教育》2019年第26期129-131,共3页China Continuing Medical Education

摘　　要：目的探究观察奥曲肽联合乌司他丁治疗急性胰腺炎效果。方法从本院2018 年1 月—2019 年1 月间接诊的急性胰腺炎患者中选取72 例纳入研究,按随机均衡原则分为两组各36 例,对照组单行奥曲肽治疗,观察组采用奥曲肽联合乌司他丁治疗,对比两组疗效。结果观察组血淀粉酶恢复正常时间、上腹压痛缓解时间以及腹痛恢复时间均短于对照组(t = 6.230、6.850、6.550),且总有效率优于对照组(χ2= 4.181),差异具有统计学意义,P < 0.05。结论奥曲肽联合乌司他丁治疗急性胰腺炎效果确切,可显著提高治疗效果,改善患者临床体征及预后,减轻炎症反应,该治疗方法有较好的应用前景,可作进一步研究分析。Objective To investigate the effect of octreotide combined with ulinastatin in the treatment of acute pancreatitis. Methods Seventy-two patients with acute pancreatitis indirectly diagnosed in our hospital from January 2018 to January 2019 were enrolled in the study. According to the principle of random equilibrium, they were divided into two groups, 36 cases in each group. The control group was treated with octreotide alone, while the observation group was treated with octreotide combined with ulinastatin. Results The recovery time of blood amylase, epigastric tenderness and abdominal pain in the observation group were shorter than those in the control group (t = 6.230, 6.850, 6.550), and the total effective rate was better than that in the control group (χ2 = 4.181). The difference was statistically significant (P < 0.05). Conclusion Octreotide combined with ulinastatin in the treatment of acute pancreatitis has definite effect, can significantly improve the treatment effect, improve the clinical signs and prognosis of patients, reduce inflammation, this treatment method has good application prospects, can be further studied and analyzed.

关 键 词：奥曲肽 乌司他丁 急性胰腺炎 疗效 效果 观察 

分 类 号：R657[医药卫生—外科学]