庆阳地区新生儿出生低血糖脑病筛查及影响因素分析  

Screening and influencing factors of neonatal hypoglycemic encephalopathy in Qingyang,Gansu Province

作　　者：田小云 王娟 张睿 TIAN Xiaoyun;WANG Juan;ZHANG Rui(Department of Neonatology,People's Hospital of Qingyang City,Qingyang 745000)

机构地区：[1]甘肃省庆阳市人民医院新生儿科

出　　处：《国外医学（医学地理分册）》2019年第3期232-234,266,共4页Foreign Medical Sciences：Section of Medgeography

摘　　要：目的探究甘肃庆阳地区新生儿出生低血糖脑病发生情况,并就其影响因素进行分析。方法选择2017年1月至2019年1月于本院分娩的291例低血糖新生儿为研究对象,分为脑病组(80例)与非脑病组(211例),对其中低血糖脑病发生率进行统计,分析可能影响新生儿低血糖性脑病发生的因素。结果①291例新生儿中有80例出现低血糖性脑病,发生率27.49%(80/291),其中男性46例,占57.50%,女性34例,占42.50%,男性新生儿与女性新生儿对比孕周差异无统计学意义(P>0.05),体质量对比男性新生儿更高(P<0.05);②脑病组新生儿中早产儿、低出生体质量儿、血糖水平<1.6mmol/L儿、母亲患有妊娠期糖尿病比率均高于非脑病组新生儿(P<0.05),同时脑病组新生儿发生病理性黄疸、感染、惊厥的概率与非脑病组新生儿比较具有统计学意义(P<0.05);③多因素分析结果显示,妊娠糖尿病、新生儿惊厥、新生儿感染、低血糖持续时间>24h是新生儿出现低血糖性脑病的独立危险因素(P<0.05)。结论庆阳地区新生儿低血糖性脑病发生率较高,分析显示妊娠糖尿病、新生儿惊厥、新生儿感染、低血糖持续时间>24h等因素可能是新生儿出现低血糖性脑病的独立危险因素,应着重实施干预,以提高新生儿出生质量。Objective To explore and analyze the incidence of neonatal hypoglycemic encephalopathy in Qingyang,Gansu Province,and to explore the influencing factors.Methods 291 hypoglycemic neonates delivered in our hospital from January 2017 to January 2019 were selected as the research objects.The incidence of hypoglycemic encephalopathy was screened and analyzed.The influencing factors of hypoglycemic encephalopathy in neonates were analyzed by differentiating encephalopathy group(80 cases) from non-encephalopathy group(211 cases).Results ①The results showed that 80 of 291 newborns had hypoglycemic encephalopathy,the incidence of which was 27.49%(80/291),of which 46 were males,accounting for 57.50%,34 were females,accounting for 42.50%.There was no significant difference in gestational weeks between male and female newborns(P>0.05),and the weight of male newborns was higher than that of male newborns(P<0.05).②The analysis showed that newborns in encephalopathy group were newborns.Premature infants,low birth weight infants,blood sugar<1.6 mmol/L infants and mothers with gestational diabetes mellitus were higher than those of non-encephalopathy infants(P<0.05),and the incidence of pathological jaundice,infection and convulsion was higher in encephalopathy infants(P<0.05).③Multivariate analysis showed that gestational diabetes mellitus,neonatal convulsion,neonatal infection and duration of hypoglycemia were longer than those of non-encephalopathy infants(P<0.05).Four hours was an independent risk factor for hypoglycemic encephalopathy(P<0.05).Conclusion The incidence of neonatal hypoglycemic encephalopathy is high in Qingyang area of Gansu Province.The analysis shows that gestational diabetes mellitus,neonatal convulsion,neonatal infection and duration of hypoglycemia >24 hours are independent risk factors for neonatal hypoglycemic encephalopathy,and intervention should be emphasized to improve the quality of neonatal birth.

关 键 词：新生儿 低血糖性脑病 影响因素 

分 类 号：R445[医药卫生—影像医学与核医学]