通脉养心丸治疗冠心病房性心律失常的临床研究  

Tongmai Yangxin Wan for atrial arrhythmias of coronary heart disease: a clinical study

作　　者：邸杰[1] 刘亮 黄少华 许巧玲[1] 陈亚伟[1] 张欣欣[1] 袁泽刚 许倩[1] Di Jie;Liu Liang;Huang Shaohua;Xu Qiaoling;Chen Yawei;Zhang Xinxin;Yuan Zegang;Xu Qian(Cardiac Intensive Care Unit, First Central Hospital of Baoding City, Hebei Province, Baoding 071000, China)

机构地区：[1]保定市第一中心医院心脏重症监护室,保定071000 [2]保定市清苑区人民医院病理科,保定071000 [3]保定市妇幼保健医院麻醉科,保定071000

出　　处：《中国循证心血管医学杂志》2019年第7期856-858,共3页Chinese Journal of Evidence-Based Cardiovascular Medicine

摘　　要：目的观察通脉养心丸治疗冠状动脉粥样硬化性心脏病(冠心病)房性心律失常中的疗效。方法收集2015年1月至2018年1月期间于保定市第一中心医院心内科住院的120例患者随机分为研究组和对照组各60例。其中,对照组予常规治疗,研究组在此基础上加用通脉养心丸,4周为一疗程。比较临床疗效、心律失常发作次数及持续时间、6 min步行距离(6MWD),记录不良反应。结果治疗后,研究组总有效率为80.0%,明显高于对照组的56.7%;与对照组相比,研究组心律失常发作次数及持续时间、6MWD均明显较优(P<0.05)。两组均无明显不良反应出现。结论通脉养心丸能有效改善冠心病房性心律失常患者的临床症状,并能提高运动耐力,值得临床推广应用。Objective To observe the curative effect of Tongmai Yangxin Wan on atrial arrhythmias of coronary heart disease(CHD). Methods The patients(n=120) were chosen from Department of Cardiology of the First Central Hospital of Baoding City in Hebei Province from Jan. 2015 to Jan. 2018, and then divided randomly into study group and control group(each n=60). The control group was given routine treatment and study group was additionally given Tongmai Yangxin Wan for 4 weeks as a course of treatment. The clinical efficacy, times and duration of arrhythmias attack and 6-minute walk distance(6MWD) were compared, and adverse reactions were recorded in 2 groups. Results After treatment, the total effective rate was 80.0% in study group, which was significantly higher than that in control group(56.7%). The times and duration of arrhythmias attack and 6 MWD were superior in study group to those in control group(P<0.05). There were no adverse reactions observed in 2 groups. Conclusion Tongmai Yangxin Wan can effectively relieve the clinical symptoms and improve exercise tolerance in patients with atrial arrhythmias of CHD, and it is worthy of clinic application.

关 键 词：通脉养心丸 冠心病 心律失常 疗效 

分 类 号：R541.4[医药卫生—心血管疾病]