血管回声跟踪技术评估多囊卵巢综合征合并胰岛素抵抗患者早期颈动脉粥样硬化  

Vascular echo tracking in evaluating early carotid atherosclerosis in patients with polycystic ovary syndrome and insulin resistance

作　　者：焦新宇 杜启亘[1] 杜昕苓 JIAO Xinyu;DU Qigen;DU Xinling(Department of Ultrasound,the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine,Harbin 150001,China)

机构地区：[1]黑龙江中医药大学附属第二医院超声科

出　　处：《中国医学影像技术》2019年第9期1327-1330,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的探讨血管回声跟踪(ET)技术评估多囊卵巢综合征合并胰岛素抵抗(PCOS-IR)患者早期颈动脉粥样硬化的应用价值。方法收集90例PCOS-IR患者,根据颈动脉内中膜厚度(CIMT)分为PCOS-IR-A组(CIMT<0.10cm,n=52)和PCOS-IR-B组(CIMT为0.10~0.15cm,n=38);另选取90名与其年龄相匹配的健康女性为对照组。采用ET技术测量颈总动脉僵硬度(β)、压力-应变弹性系数(Ep)、单点脉搏波传导速度(PWVβ)、增大指数(AI)和顺应性(AC),比较3组间的差异。结果PCOS-IR-A组、PCOS-IR-B组与对照组间β、Ep、PWVβ、AC总体差异均有统计学意义(P均<0.05),AI差异无统计学意义(P=0.250)。PCOS-IR-B组β、Ep、PWVβ均高于、AC值低于对照组和PCOS-IR-A组,PCOS-IR-A组β、Ep、PWVβ均高于、AC值低于对照组,差异均有统计学意义(P均<0.05)。结论ET技术能够定量评估颈动脉各弹性参数,及早发现PCOS-IR患者早期颈动脉粥样硬化等血管弹性功能异常,为临床及早干预提供重要依据。Objective To observe the value of vascular echo tracking (ET) in evaluating early carotid atherosclerosis in patients with polycystic ovary syndrome complicated with insulin resistance (PCOS-IR).Methods According to the carotid intima-media thickness (CIMT),totally 90 patients with PCOS-IR were divided into PCOS-IR-A group (CIMT<0.10 cm,n =52) and PCOS-IR-B group (CIMT 0.10-0.15 cm,n =38).Meanwhile,90 age-matched healthy women were enrolled as control group.The stiffness degree (β),pressure-strain elasticity modulus (Ep),single point pulse wave conduction velocity (PWVβ),augmentation index (AI) and arteria compliance (AC) of common carotid artery were measured with ET and compared among 3 groups.Results There were significant differences of β,Ep,PWVβ and AC among PCOS-IR-A group,PCOS-IR-B group and control group (all P <0.05),while there was no significant difference of AI ( P =0.250).β,Ep and PWVβ in PCOS-IR-B group were higher,while AC was lower than those in control group and PCOS-IR-A group.β,Ep and PWVβ in PCOS-IR-A group were higher,while AC was lower than those in control group (all P <0.05).Conclusion ET technique can be used to quantitatively evaluate the elastic parameters of carotid artery.Vascular elastic dysfunction in early carotid atherosclerosis in patients with PCOS-IR can be early detected,therefore providing important evidences for early clinical intervention of PCOS-IR.

关 键 词：多囊卵巢综合征 胰岛素抗药性 回声跟踪 动脉粥样硬化 超声检查 

分 类 号：R711.75[医药卫生—妇产科学] R445.1[医药卫生—临床医学]