1500例输血患者红细胞血型不规则抗体分析  

Analysis of irregular antibody of RBC blood group in 1500 patients undergoing blood transfusion

作　　者：牛怀瑛 郝肖伟 NIU Huai-ying;HAO Xiao-wei(the People's Hospital of Zhidan County,Yan'an 717500;Xianyang Rainbow Hospital,Xianyang 712000,China)

机构地区：[1]志丹县人民医院,陕西延安717500 [2]咸阳彩虹医院,陕西咸阳712000

出　　处：《临床医学研究与实践》2019年第27期121-122,共2页Clinical Research and Practice

摘　　要：目的分析我院1 500例输血患者不规则抗体检测结果。方法应用微柱凝胶法对在我院行输血治疗的1 500例患者进行不规则抗体检测,分析其不规则抗体检测结果。结果经筛查共发现不规则抗体检测阳性者38例,占比为2.53%,凝集强度为1+~3+,抗体效价为1∶4~1∶16。女性、有妊娠史女性、有输血史患者的不规则抗体阳性率分别显著高于男性、无妊娠史女性和无输血史患者(P<0.05)。所检出38例不规则抗体中,Rh系统所占比例最高,其次为MNS系统。Rh系统中,抗-E阳性占比最高,其次为抗-Ce。结论输血前进行不规则抗体检测有助于了解患者的抗体类型,尤其是对于有输血史的患者,可以提高输血安全性。Objective To analyze the results of irregular antibody detection in 1 500 patients undergoing blood transfusion in our hospital. Methods Microcolumn gel method was used to detect irregular antibody in 1 500 patients undergoing blood transfusion in our hospital, and the results of irregular antibody detection were analyzed. Results A total of 38 irregular antibody positive cases were found by screening, accounting for 2.53%, the agglutination intensity was 1+-3+, and the titer of antibody was 1∶4-1∶16. The positive rates of irregular antibody in women, women with pregnancy history and patients with blood transfusion history were significantly higher than those in men, women without pregnancy history and patients without blood transfusion history(P<0.05). Among the 38 irregular antibodies detected, Rh system accounted for the highest proportion, followed by MNS system. In Rh system, anti-E has the highest positive rate, followed by antiCe. Conclusion Irregular antibody detection before blood transfusion is helpful to understand the types of antibodies in patients, especially for patients with a history of blood transfusion, which can improve the safety of blood transfusion.

关 键 词：不规则抗体 输血 微柱凝胶法 

分 类 号：R446.6[医药卫生—诊断学]