观察糖皮质激素治疗间质性肺病急重症的效果  

Effect of Glucocorticoid on Acute and Severe Pulmonary Disease

作　　者：卢晓来[1] 尹虹雷[1] LU Xiaolai;YIN Honglei(Department of Respiratory Medicine,Nangang Hospital,Heilongjiang Provincial Hospital,Harbin Heilongjiang 150001,China)

机构地区：[1]黑龙江省医院南岗院区呼吸内科

出　　处：《中国卫生标准管理》2019年第17期60-61,共2页China Health Standard Management

摘　　要：目的探讨分析糖皮质激素对于间质性肺病急重症的治疗效果。方法选取2017年1月-2018年12月在我院接受治疗的80例间质性肺病急重症患者作为研究对象,根据治疗方法不同分为观察组(n=40)和对照组(n=40)。对照组给予常规治疗,观察组在此基础上联合糖皮质激素治疗。比较两组患者的治疗有效率以及血气指标。结果观察组患者的治疗总有效率显著高于对照组(P<0.05);治疗后,观察组患者的PaO2与PaO2/FiO2显著高于对照组,PaCO2显著低于对照组,差异均具有统计学意义(P<0.05)。结论糖皮质激素治疗间质性肺病急重症的疗效确切,可以有效改善患者各项肺功能指标,促进疾病康复,在临床中值得大力推广与应用。Objective To analyze the therapeutic effect of glucocorticoids on acute and severe pulmonary disease. Methods Eighty patients with severe acute disease of interstitial lung disease who were treated in our hospital from January 2017 to December 2018 were enrolled. The patients were divided into observation group(n=40) and control group(n =40) according to different treatment methods. The control group was given conventional treatment, and the observation group was treated with glucocorticoid on this basis. The total effective rate and blood gas level were compared between the two groups. Results The total effective rate of the observation group was significantly higher than that of the control group(P < 0.05). After treatment, PaO2 and PaO2/FiO2 of the observation group were significantly higher than the control group, PaCO2 was significantly lower than the control group, and the difference was statistically significant(P < 0.05). Conclusion Glucocorticoid is effective in the treatment of acute and severe pulmonary disease. It can effectively improve various lung function indexes and promote disease rehabilitation. It is worthy of promotion and application in clinical practice.

关 键 词：糖皮质激素 间质性肺病 急重症 血气分析 疗效 血氧分压 

分 类 号：R563[医药卫生—呼吸系统]