体外冲击波穴位治疗对肩关节周围炎患者肩部疼痛及血清5- HT、PGE2影响的临床观察  

Clinical observation on effect of extracorporeal shock wave acupoint therapy on shoulder pain and levels of serum 5- HT and PGE2 in patients with shoulder periarthritis

作　　者：任佳悦 杨燕冰 季晶俊[1] 徐玉萍[1] REN Jiayue;YANG Yanbing;JI Jingjun;XU Yuping(Department of Geriatrics, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200021, China)

机构地区：[1]上海中医药大学附属曙光医院老年科

出　　处：《上海中医药杂志》2019年第8期68-71,共4页Shanghai Journal of Traditional Chinese Medicine

基　　金：上海市卫计委进一步加快中医药事业发展三年行动计划项目(ZY3-CCCX-3-3028)

摘　　要：目的观察体外冲击波穴位治疗对肩关节周围炎患者肩部疼痛及血清5-羟色胺(5-HT)、前列腺素E2(PGE2)水平的影响。方法将82例肩关节周围炎患者随机分为治疗组与对照组,每组41例。对照组采用常规体外冲击波局部治疗,治疗组采用体外冲击波穴位治疗。两组疗程均为4周,观察临床疗效,比较肩部疼痛VAS评分、肩关节活动度及血清5-HT、PGE2水平的变化情况。结果①试验期间无病例脱落。②治疗组、对照组总有效率分别为97.56%、80.49%;组间临床疗效比较,治疗组明显优于对照组(P<0.05)。③治疗前后组内比较,两组肩部VAS疼痛评分均明显降低(P<0.05);组间治疗前后肩部VAS疼痛评分差值比较,治疗组明显大于对照组(P<0.05)。④治疗前后组内比较,两组肩关节活动度(各分项)均明显增大(P<0.05);组间治疗前后肩关节活动度(各分项)差值比较,治疗组明显大于对照组(P<0.05)。⑤治疗前后组内比较,两组血清5-HT和PGE2水平均明显降低(P<0.05);组间治疗前后血清5-HT和PGE2水平差值比较,治疗组明显大于对照组(P<0.05)。结论体外冲击波穴位治疗对肩关节周围炎患者的疗效较佳,可减轻肩部疼痛,提高肩关节活动度,降低血清PGE2和5-HT水平。Objective To investigate the effect of extracorporeal shock wave acupoint therapy on shoulder pain and the levels of serum 5-hydroxytryptamine(5-HT) and prostaglandin E2(PGE2) in patients with shoulder periarthritis. Methods 82 patients with shoulder periarthritis were randomly assigned into treatment group and control group, 41 patients in each group. The control group was treated with routine extracorporeal shock wave therapy, while the treatment group was treated with extracorporeal shock wave acupoint therapy. The treatment course was 4 weeks. The therapeutic effect was observed. Changes in VAS score of shoulder pain, shoulder range of motion as well as levels of serum 5-HT and PGE2 were compared. Results ①There was no drop-out during the trial.②The total effective rate was significantly higher in the treatment group(97.56%) than in the control group(80.49%)(P<0.05).③After treatment, the VAS scores of shoulder pain decreased in both groups(P<0.05);and the difference in the scores before and after treatment were greater in the treatment group than in the control group(P<0.05).④After treatment, the shoulder range of motion increased significantly in both groups(P<0.05);and the difference in shoulder range of motion before and after treatment was greater in the treatment group than in the control group(P<0.05).⑤After treatment, the levels of serum 5-HT and PGE2 decreased significantly in both groups(P<0.05);and the differences in the levels before and after treatment were greater in the treatment group than in the control group(P<0.05). Conclusion Extracorporeal shock wave acupoint therapy is effective in patients with shoulder periarthritis as it relieves shoulder pain, increases shoulder range of motion and reduces the levels of PGE2 and 5-HT in serum.

关 键 词：肩关节周围炎 体外冲击波 穴位治疗 肩关节活动度 5-羟色胺 前列腺素E2 

分 类 号：R684[医药卫生—骨科学]