中医药对哮喘Th17/Treg失衡作用机制研究进展  

Research progress on mechanism of action of TCM in Th17/Treg imbalance in asthma

作　　者：邱丹丹 孙剑玥[2] 杨子珍[2] 解玉[2] 蔡蕙荞 QIU Dandan;SUN Jianyue;YANG Zizhen;XIE Yu;CAI Huiqiao(Putuo Clinical Medical College in Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China;Pediatrics Department, Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China)

机构地区：[1]上海中医药大学普陀临床医学院,上海200062 [2]上海中医药大学附属普陀医院儿科,上海200062

出　　处：《上海中医药杂志》2019年第8期98-101,共4页Shanghai Journal of Traditional Chinese Medicine

基　　金：上海市卫计委中医薄弱领域专科建设项目——中医儿科(A-265);上海中医药大学研究生创新培养专项项目(h-2018-研究生项目)

摘　　要：综述中医药对哮喘Th17/Treg失衡作用机制研究进展。Th17/Treg失衡在哮喘发病机制中有重要作用,研究表明中药单体(黄芩苷、淫羊藿苷等)、多种复方(固本防哮汤、平喘方等)、外治法(针灸)可通过调节Th17/Treg细胞数量、相关炎症因子等,减轻气道炎症,改善哮喘症状。This paper reviews the research progress on the mechanism of action of TCM in Th17/Treg imbalance in asthma. Th17/Treg imbalance plays an important role in the pathogenesis of asthma. It has been shown that in traditional Chinese medicine, herbal monomers(baicalin, icariin, etc.), a variety of compounds(Guben Fangxiao Decoction, Pingchuan Formula, etc.) and external treatment(acupuncture and moxibustion) can reduce airway inflammation and improve asthma symptoms by regulating the number of Th17/Treg cells and the relevant inflammatory cytokines.

关 键 词：支气管哮喘 TH17 TREG 中医 综述 

分 类 号：R256.12[医药卫生—中医内科学]