笑气清醒镇痛在结肠镜检查中的疗效及安全性研究  

Study on the efficacy and safety of nitrous oxide inhalation conscious analgesia in colonoscopy

作　　者：唐斌[1] 张俊[1] 蒋波[1] 唐友攀 李月平[1] 王人彬 舒欧 罗华 Tang Bin;Zhang Jun;Tang Youpan;Li Yueping;Wang Renbin;Shu Ou;Luo Hua(Department of Gastroenterology,the People's Hospital of Zhongjiang County,Sichuan Province 618100)

机构地区：[1]四川省中江县人民医院消化内科

出　　处：《中国社区医师》2019年第27期52-54,共3页Chinese Community Doctors

基　　金：四川省德阳市科知局重点科技计划项目(项目编号：2018SZS102)~~

摘　　要：目的:探讨笑气清醒镇痛在结肠镜检查中的疗效及安全性。方法:收治接受结肠镜检查的患者400 例,分为两组,各200 例。观察组实施笑气吸入清醒镇痛,对照组实施丙泊酚静脉麻醉,比较两组镇痛效果和血氧饱和度下降、心动过缓等相对严重的不良反应方面的差异。结果:两组镇痛有效率比较,差异无统计学意义(χ2=4.040,P>0.05);观察组相对严重的不良反应发生率较对照组低,差异有统计学意义(χ2=17.755,P<0.05)。结论:笑气吸入清醒镇痛应用于结肠镜检查术中的镇痛效果好且安全性高。Objective:To investigate the efficacy and safety of nitrous oxide inhalation conscious analgesia in colonoscopy. Methods:400 patients underwent colonoscopy were selected,they were divided into two groups with 200 cases in each group.The observation group received awake analgesia with inhalation of nitrous oxide and the control group received intravenous anesthesia with propofol.The differences of analgesia effect and fairly serious adverse reaction were compared between colonic adenomatous polyps group and the control group,the fairly serious adverse reaction such as decrease in oxygen saturation,bradycardia and so on. Results:There was no statistical difference in analgesia effect between the observation group and the control group,the difference was statistically significant(χ 2=4.040,P<0.05).The incidence of fairly serious adverse reactions of the observation group was significantly lower than that in the control group,and the difference was statistically significant(χ2=17.755,P<0.05).Conclusion: Nitrous oxide inhalation was effective and safe for conscious analgesia in colonoscopy.

关 键 词：结肠镜检查 笑气 丙泊酚 镇痛 

分 类 号：R614[医药卫生—麻醉学] R574.62[医药卫生—外科学]