绵萆薢化学成分研究(Ⅱ)  

Study on the chemical composition of Dioscorea septemloba Thunb.

作　　者：邓旭坤[1] 余惠凡 刘钊 舒广文[1] 郑燕[3] 段欢[1] DENG Xukun;YU Huifan;LIU Zhao;SHU Guangwen;ZHENG Yan;DUAN Huan(School of Pharmaceutical Sciences,South-Central University for Nationalities,Wuhan 430074,China;Editorial Department of University Journal,South-Central University for Nationalities,Wuhan 430074,China;Department of Medicine,Huaibei Vocational and Technical College,Huaibei 235000,China)

机构地区：[1]中南民族大学药学院,武汉430074 [2]中南民族大学学报编辑部,武汉430074 [3]淮北职业技术学院医学系,淮北235000

出　　处：《中南民族大学学报（自然科学版）》2019年第3期411-414,共4页Journal of South-Central University for Nationalities：Natural Science Edition

基　　金：国家自然科学基金资助项目(81073147);国家科技部“十二五”科技支撑计划资助项目(2012BAI27B06)

摘　　要：采用现代分离技术对绵萆薢的化学成分进行了分离纯化,并用波谱技术鉴定其结构.结果从该植物提取物中分离得到8个化合物,分别为:对羟基苯乙酮(1)、4-(对羟基苯基)-2-丁酮(2)、肉桂酸(3)、对羟基苯乙醇(4)、苯酚(5)、1-β-D-呋喃核糖基-1H-1,2,4-三氮唑(6)、薯蓣皂苷元-3-O-[α-L-吡喃鼠李糖(1→2)]-[α-L-吡喃鼠李糖(1→4)]-β-D-吡喃葡萄糖(7)、薯蓣皂苷元-3-O-[α-L-吡喃鼠李糖(1→2)]-β-D-吡喃葡萄糖(8).其中化合物1~6为首次从该植物分离得到,且化合物1、4、5、6是首次从该属植物中分离得到.The modern separation techniques were applied to sepearating and purifying the chemical constituents of Dioscorea septemloba Thunb.,and spectroscopic technique was used to elucidate its structure.8 compounds were obtained and identified as 4′-hydroxyacetophenone(1),1-(4-hydroxyphenyl)-1-butanone(2),trans-cinnamic acid(3),4-hydroxyphenethyl alcohol(4),phenol(5),1-(β-D-ribofuranosyl)-1H-1,2,4-triazone(6),diosgenin bis-(α-L-rhamnopyranosyl)-(1→2 and 1→4)-β-D-glucopyranoside(7),diosgenin-3-O-α-L-rhamnopyranosyl(1→2)-β-D-glucopyranoside(8).Compounds 1-6 were separated and obtained for the first time from this plant,moreover,compounds 2,4,5 and 6 were separated and obtained from this genus for the first time.

关 键 词：绵萆薢 乙酸乙酯部位 化学成分 

分 类 号：O629[理学—有机化学] R284.1[理学—化学]