妊娠期ABO抗体阳性的研究进展  

Progress in research of ABO antibody positive during pregnancy

作　　者：贾丹[1] 蒋莎 李娜[1,2] 冯晓玲(指导)[1,2] JIA Dan;JIANG Sha;LI Na;FENG Xiao-Ling(Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学,哈尔滨150040 [2]黑龙江中医药大学附属第一医院,哈尔滨150040

出　　处：《中国免疫学杂志》2019年第18期2302-2304,F0003,F0004,共5页Chinese Journal of Immunology

摘　　要：我国ABO母儿血型不合占新生儿溶血病的96%,占新生儿黄疸的28.6%。母儿ABO血型不合容易引起胎儿或新生儿溶血病。本病常发生在O型RhD阳性血型(其配偶血型非O型)的孕妇中。孕妇ABO抗体阳性者早期流产率高,易诱发早产、胎儿宫内生长受限、易发生胎儿贫血、水肿、溶血,引起新生儿早发性黄疸、新生儿溶血或核黄疸等后遗症,甚至死亡。本文对妊娠期ABO抗体阳性的治疗和管理进行论述。ABO incompatibility accounts for 96%of neonatal hemolysis in China,accounting for 28.6%of neonatal jaundice.Maternal and infant ABO blood group incompatibility is easy to cause fetal or neonatal immune hemolytic diseases.Maternal and infant incompatibilities often occur in pregnant women with type O RhD positive blood types(The spouse is not type O).Pregnant women with positive ABO antibodies have a high rate of early miscarriage,and are prone to preterm birth,intrauterine growth restriction,fetal anemia,edema,hemolysis,early neonatal jaundice,neonatal hemolysis or nuclear jaundice,and even death.The treatment and management of ABO-positive antibodies during pregnancy were discussed.

关 键 词：母儿血型不合 ABO血型系统 不良妊娠结局 治疗 

分 类 号：R714.2[医药卫生—妇产科学]