300例特发性间质性肺炎患者生活质量现状及影响因素分析  

Analysis on present situation of quality of life and its influencing factors of 300 cases of patients with idiopathic interstitial pneumonia

作　　者：王艳军[1,2] 曲丹华[1] 郭昕[3] 姚燕[3] 程远娟[2] WANG Yanjun;QU Danhua;GUO Xin;YAO Yan;CHENG Yuanjuan(Department of Respiratory Medicine,Second Hospital, Jilin University,Changchun 130041,China;Department of Nursing,Second Hospital, Jilin University,Changchun 130041,China;Department of Epidemiology and Health Statistics,School of Public Health,Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学第二医院呼吸内科,吉林长春130041 [2]吉林大学第二医院护理部,吉林长春130041 [3]吉林大学公共卫生学院流行病与卫生统计学教研室,吉林长春130021

出　　处：《吉林大学学报（医学版）》2019年第5期1119-1127,共9页Journal of Jilin University：Medicine Edition

基　　金：吉林省科技发展计划项目国际合作项目资助课题(20140414066GH)

摘　　要：目的:探讨影响特发性间质性肺炎(IIP)患者生活质量的相关影响因素,为提高IIP患者生活质量、预防其他并发症和改善患者预后提供理论依据。方法:采用圣乔治呼吸问卷(SGRQ)评估住院治疗且符合纳入及排除标准的300例IIP患者的生活质量;比较不同特征人群之间各维度生存质量评分的差异;采用一般线性回归模型筛选可能影响各维度生活质量评分的独立影响因素。结果:饮酒、用力肺活量(FVC)和6min步行试验(6MWT)是IIP患者症状评分的独立影响因素(P<0.05);民族、家庭人均月收入、肺一氧化碳弥散量(DLCO)和6MWT是IIP患者活动受限评分的独立影响因素(P<0.05);民族、家庭人均月收入、FVC和6MWT是IIP患者生活影响评分的独立影响因素(P<0.05);民族、家庭人均月收入、FVC和6MWT是IIP患者生活质量总分的独立影响因素(P<0.05)。结论:IIP患者活动受限较为明显,饮酒、民族、家庭人均月收入、FVC、6MWT和DLOC是影响IIP患者不同维度生活质量的影响因素。Objective : To explore the influencing factors related to the quality of life of the patients with idiopathic interstitial pneumonia (IIP), and to provide the theoretical basis for improving the quality of life, preventing other complications,and improving the prognosis of the patients with IIP. Methods : St George’s Respiratory Questionnaire (SGRQ) was used to evaluate the quality of life of 300 hospitalization patients with IIP who met the inclusion criteria in the study. The differences of quality of life among different groups of people were compared. A general linear regression model was used to screen the independent influencing factors that may affect the scores of quality life of all dimensions. Results : Drinking, forced vital capacity (FVC) and 6 min walk test (6MWT) were the independent influencing factors of the symptom score of the IIP patients ( P <0.05);nation, family per capita monthly income, carbon monoxide diffusion capacity (DLCO), and 6MWT were the independent influencing factors of activity limit score of the IIP patients ( P <0.05);nation, family per capita monthly income, FVC, and 6MWT were the independent influencing factors of life impact score of the IIP patients ( P <0.05);nation, family per capita monthly income, FVC, and 6MWT were the independent influencing factors of the scores of quality of lif e of the IIP patients ( P <0.05). Conclusion : The activity limit of IIP patients is more obvious. Drinking, nation and family per capita monthly income, FVC, 6MWT and DLOC are the factors affecting the quality of life of the IIP patients in different dimensions.

关 键 词：特发性间质性肺炎 圣乔治呼吸问卷 生活质量 肺功能 影响因素 

分 类 号：R563.13[医药卫生—呼吸系统]