噬菌体治疗海水养殖动物常见细菌性疾病的研究进展  

Research Progress of Using Bacteriophages in Treatment of Common Bacterial Diseases in Marine Cultured Animals

作　　者：崔惠敬 耿慧君 王丽丽[1,2,4] 李晓宇 李淑英[2,3,4] 徐永平 Cui Hui-jing;Geng Hui-jun;Wang Li-li;Li Xiao-yu;Li Shu-ying;Xu Yong-ping(School of Bioengineering,Dalian University of Technology,Dalian 116024;Center for Food Safety of Animal Origin,Ministry of Education,Dalian 116000;Dalian SEM Bio-Engineering Technology Co. Ltd.,Dalian 116020;Center for Phage Applied Engineering Technology of Dalian SEM,Liaoning Province,Dalian 116600)

机构地区：[1]大连理工大学生物工程学院,大连116024 [2]教育2部动物性食品安全保障技术工程研究中心,大连116600 [3]大连赛姆生物工程技术公司,大连116620 [4]辽宁省大连赛姆噬菌体应用工程技术研究中心,大连116600

出　　处：《国外医药（抗生素分册）》2019年第5期445-450,共6页World Notes on Antibiotics

基　　金：国家海洋公益项目(201405003-3)

摘　　要：水产养殖业是世界上发展最快的行业之一,在经济发展中占有非常重要的地位。中国是世界第一水产养殖大国,但规模化和集约化养殖导致鱼类病害频发。抗生素及化学药物的应用正被日渐限制,这给水产动物病害防治带来新的挑战。噬菌体是一种细菌依赖性病毒,是自然界中丰富度最高的一种生物类群。与抗生素相比,噬菌体具有来源广泛、自我复制繁殖能力强、特异性强、安全性高、无毒无害、与生态友好等优势。本论文就噬菌体在海水养殖中的研究概况及最新研究进展作一综述,旨在为海水动物病害防治提供新思路。Aquaculture is one of the fastest growing industries in the world and occupies a very important position in economic development.China has the largest aquaculture industry in the world.However,largescale intensive aquaculture has resulted in frequent outbreaks diseases.The application of feed antibiotics and chemical drugs is becoming more restricted,which presents a great challenge for disease prevention in aquaculture.Bacteriophage is a bacterial-dependent virus and is the most abundant biota in nature.Compared with antibiotics,phage has a wide range of sources,self-reproduction and reproductive ability,specificity,safety,non-toxic harmless,and eco-friendly advantages.In this article reviewed the current research on the use of phage in aquaculture,with the aim of providing new insights into the green aquaculture.

关 键 词：水产养殖 细菌 抗生素 噬菌体 

分 类 号：R978.19[医药卫生—药品]