银屑病的神经免疫学研究进展  

Research Progress of Neuroimmunology in Psoriasis

作　　者：郝志敏 顾恒[1] 陈敏[1] HAO Zhimin;GU Heng;CHEN Min(Institution of Dermatology,Chinese Academy of Medical Sciences and Peking Union Medical College,Nanjing 210042,China)

机构地区：[1]中国医学科学院北京协和医学院皮肤病研究所

出　　处：《中国皮肤性病学杂志》2019年第10期1206-1209,共4页The Chinese Journal of Dermatovenereology

基　　金：北京协和医学院教学科研项目(2016,06-2019,05);中国医学科学院医学与健康科技创新工程重大协同创新项目(CIFMS-2017-12M-1-017)

摘　　要：银屑病是一种慢性炎症性皮肤病,其病因尚未完全阐明。心理应激因素通过中枢神经系统、外周神经系统和皮肤下丘脑-垂体-肾上腺素轴,参与对银屑病的神经免疫调节。神经免疫调节机制的探究对心理应激诱导银屑病发病机制的阐明有重要意义。Psoriasis is a chronic inflammatory skin disease. The etiology of psoriasis has not been fully elucidated. It has been proposed that psychological stress regulates neuroimmune function in psoriasis via influencing the central nervous system, peripheral nervous system and skin hypothalamic-pituitary-adrenalin axis. Exploration of the regulatory mechanisms of neuroimmunity is crucial for elucidating pathogenesis of stress-induced psoriasis.

关 键 词：银屑病 应激 神经免疫学 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]