早产儿原发性雷诺现象一例  

Primary Raynaud's phenomenon in premature infant: a case report

作　　者：朱巍巍[1] 刘云峰[1] 朴梅花[1] 王晶[1] 王丽娟[1] 李蕊[1] Zhu Weiwei;Liu Yunfeng;Piao Meihua;Wang Jing;Wang Lijuan;Li Rui(Department of Pediatrics,Peking University Third Hospital,Beijing 100191,China)

机构地区：[1]北京大学第三医院儿科,100191

出　　处：《中华围产医学杂志》2019年第9期648-651,共4页Chinese Journal of Perinatal Medicine

摘　　要：本文报道1例新生儿原发性雷诺现象的诊断及治疗。患儿为30周^+3早产儿,生后第5天无明显诱因出现右手齐腕部至远端完全苍白,桡动脉搏动弱,皮温较对侧降低,予按摩右上肢、保暖、静脉滴注前列腺素E1、外敷多磺酸黏多糖乳膏后,右手逐渐由苍白转为青紫,后逐渐恢复红润。完善可导致继发性雷诺现象的检查均未见异常,考虑原发性雷诺现象。住院期间及后期随访过程中患儿均未复发。此病例较少见,若临床中患儿出现双手突然苍白,后青紫,需注意有无雷诺现象。治疗方面,主要以去除病因、保暖、按摩病变部位的上肢为主,必要时可应用药物改善外周循环。此类患儿需长期随访。This is a case report of preterm female neonate with Raynaud's phenomenon, who was born at 30^+3 weeks of gestation. Her right upper limb completely turned pale from wrist to fingers with undetermined cause five days after birth, with weakened radial artery pulsation and lower skin temperature than the other side. After several treatment steps including right upper limb massage, keeping warm, intravenous infusion of Alprostadil and application of tropical mucopolysaccharide polysulfate cream, the affected limb gradually turned to purple and then ruddy. No abnormality was detected in the examinations for secondary Raynaud's phenomenon, therefore a primary Raynaud's phenomenon was considered. No similar symptoms recurred during hospitalization or follow-ups. Though rare, Raynaud's phenomenon should be considered if patients' hands suddenly turn to pale and then purple. The main treatments involve removing the causative factors, keeping warm and massage of the affected limb. Medications can be used to improve peripheral circulation if necessary. Long-term follow-up is needed for neonates suffered from Raynaud's phenomenon.

关 键 词：雷诺现象 婴儿 早产 治疗 

分 类 号：R722.6[医药卫生—儿科]