机构地区:[1]中南大学湘雅二医院临床护理学教研室,长沙410003 [2]中南大学湘雅二医院血液内科,长沙410003
出 处:《中华现代护理杂志》2019年第25期3268-3271,共4页Chinese Journal of Modern Nursing
摘 要:目的探讨腹部轮换定时定位注射卡在多发性骨髓瘤(MM)患者皮下注射中的应用效果。方法选取中南大学湘雅二医院血液内科2017年7月—2018年7月住院的90例MM患者为研究对象,按照随机数字表法分为观察组与对照组,每组各45例。两组患者均进行硼替佐米腹部皮下注射治疗,对照组采取常规腹部皮下注射,观察组应用腹部轮换定时定位注射卡进行皮下注射,干预4个疗程后,比较两组患者的疼痛部位视觉模拟评分(VAS)、注射部位不良反应发生率、单次给药耗时。结果最终观察组43例、对照组42例患者完成研究。干预后,观察组的VAS得分为(3.69±0.93)分,低于对照组的(4.99±1.27)分,两组得分比较差异有统计学意义(P<0.05);观察组注射部位不良反应发生率为6.20%(45/724),低于对照组的12.80%(89/696),两组比较差异有统计学意义(P<0.05);观察组的单次给药耗时为(7.77±0.60)min,少于对照组的(8.38±0.57)min,两组比较差异有统计学意义(P<0.05)。结论腹部轮换定时定位注射卡在MM患者皮下注射的应用中,与常规腹部皮下注射相比,可以减轻患者注射部位疼痛感,减少注射部位不良反应发生,减少护理操作用时,提高护士工作效率,且制作简单,可在临床护理工作中推广应用。Objective To explore the effects of abdominal rotation timing and positioning card on subcutaneous injection for patients with multiple myeloma (MM). Methods Totally 90 MM patients hospitalized in the department of Hematology, the Second Xiangya Hospital of Central South University from July 2017 to July 2018 were selected and stratified into observation (n=45) and control (n=45) groups according to the random number table. Patients in both groups were injected with Bortezomib through the abdomen subcutaneously. Patients in the control group received conventional subcutaneous injection, while patients in subcutaneous injection using the abdominal rotation timing and positioning card. Visual Analogue Scale (VAS) scores, incidence rate of adverse effects at the injection site and time of single administration were compared between the two groups after 4 courses of treatment. Results Totally 43 patients from the observation group and 42 patients from the control group completed the study. The VAS score was (3.69±0.93) in the observation group, lower than (4.99±1.27) in the control group, and there was statistically significant difference between the two groups post intervention (P<0.05). The incidence rate of adverse effects at the injection site was 6.20%(45/724) in the observation group, lower than 12.80%(89/696) in the control group, and there was statistically significant difference between the two groups post intervention (P<0.05). The time of single administration was (7.77±0.60) min in the observation group, shorter than (8.38±0.57) min in the control group, and there was statistically significant difference between the two groups post intervention (P<0.05). Conclusions Compared with conventional abdominal subcutaneous injection, the use of the abdominal rotation timing and positioning card in subcutaneous injection for MM patients may reduce the sense of pain and the incidence of adverse effects at the injection site as well as the time for nursing operation, and improve nurses' working efficiency, which
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