无创血流储备分数临床应用的研究进展  

Progress in clinical application of fractional flow reserve derived from computed tomographic angiography

作　　者：姚翔 邢波[1] YAO Xiang;XING Bo(Department of Cardiology,Haikou Hospital Affiliated to Xiangya School of Medicine,Central South University,Haikou 570100,China)

机构地区：[1]中南大学湘雅医学院附属海口医院心血管内科

出　　处：《中南大学学报（医学版）》2019年第9期1078-1082,共5页Journal of Central South University ：Medical Science

摘　　要：冠状动脉缺血的评估在冠心病的诊治中具有重要意义。近年来,一项基于无创冠状动脉CT造影的血流储备分数(fractional flow reserve derived from computed tomographic angiography,FFRct)用以评估冠状动脉特异性缺血的诊断技术的出现,丰富了冠状动脉疾病患者的临床管理。已有多项研究证实FFRct较血流储备分数(fractional flow reserve,FFR)具有更可靠的诊断性能。由于FFRct无创性、可重复测量等优势,使得FFRct的应用普遍性明显高于有创生理学检查。同时,FFRct的应用范围也在不断拓展,不局限于其侵入性造影检查“看门人”的地位。其对冠状动脉复杂病变患者的诊断具有较好的准确性,亦可用于指导冠状动脉旁路移植术和支架植入术等手术治疗策略的选择。The evaluation of coronary artery ischemia is of great significance in the diagnosis and treatment of coronary heart disease.In recent years,fractional flow reserve derived from computed tomographic angiography (FFRct) has been used to evaluate the diagnosis of coronary artery specific ischemia, which enriches the clinical management of patients with coronary artery disease.A number of studies have confirmed that FFRct has reliable diagnostic performance compared with invasive fraction flow reserve (FFR).Because of its non-invasive,repeatable measurement and other advantages,the application universality of FFRct is significantly higher than that of invasive examination.At the same time,the application scope of FFRct is also continuously expanding, and it is not limited to its position as a “gatekeeper” for invasive coronary angiography.It has good accuracy in the diagnosis of complex coronary artery disease,and can also be used to guide the choice of surgical strategies such as coronary artery bypass grafting and stent implantation.

关 键 词：冠心病 无创冠状动脉CT造影的血流储备分数 复杂病变 血运重建 

分 类 号：R541.4[医药卫生—心血管疾病]