镇痛镇静治疗的脏器保护作用  

The protection effect of organ function of analgesic and sedative therapy

作　　者：戚智冬[1] 杨斯博[2] 郜杨[1] Qi Zhi-dong;Yang Si-bo;Gao Yang(Intensive Care Unit, the Second Affiliated Hospital of Harbin Medical University, Harbin 150086, China)

机构地区：[1]哈尔滨医科大学附属第二医院重症医学科,黑龙江哈尔滨150086 [2]哈尔滨医科大学附属第一医院儿内科,黑龙江哈尔滨150001

出　　处：《中国急救医学》2019年第9期908-912,共5页Chinese Journal of Critical Care Medicine

摘　　要：ICU患者时刻处于强烈的应激环境中,镇痛镇静治疗通过缓解患者的不适,可以减少伤害性刺激,已经成为ICU综合治疗中的重要组成部分。此外,镇痛镇静治疗可以发挥脏器保护作用,诸如调控应激,减轻炎症反应和缺血/再灌注损伤,减少氧耗和氧需,降低患者的代谢率,为器官功能的恢复赢得时间、创造条件。ICU patients are in the intense stress environment. Analgesic and sedative treatment can relieve the discomfort and reduce harmful stimulus of patients, therefore it has become an important component of comprehensive treatment in the ICU. In addition, there are some protecting effects on organ, such as regulating and controlling stress response, reducing inflammation and ischemia - reperfusion injury, decreasing oxygen consumption and oxygen demand, lowering metabolic rate. So it can create conditions for organ function recovery.

关 键 词：镇痛镇静治疗 脏器功能保护 多器官功能障碍 

分 类 号：R459.7[医药卫生—急诊医学]