调督熄风针法对肝阳上亢非杓型高血压病患者的影响  

Effect of Tiaodu Xifeng acupuncture on non-dipper hypertension patients with syndrome of upper hyperactivity of liver yang

作　　者：梁燕[1] 鲍晓华 李晨梅 高慧[1] 王艳君[4] 李佳[5] 刘田莉 LIANG Yan;BAO Xiaohua;LI Chenmei;GAO Hui;WANG Yanjun;LI Jia;LIU Tianli(The Third Cardiology Department,Shijiazhuang Hospital of Traditional Chinese Medicine,Hebei Province,Shijiazhuang 050021,China;Gynecology and Obstetrics Department,Fengning Manchu Autonomous County Hospital of Traditional Chinese Medicine in Chengde City,Hebei Province,Fengning 068350,China;Anus-intestines Department,Shijiazhuang Hospital of Traditional Chinese Medicine,Hebei Province,Shijiazhuang 050021,China;Acupuncture Department,Hebei Province Hospital of Traditional Chinese Medicine,Hebei Province,Shijiazhuang 050011,China;Graduate School,Hebei North University,Hebei Province,Zhangjiakou 075000,China)

机构地区：[1]石家庄市中医院心三科,河北石家庄050021 [2]河北省承德市丰宁满族自治县中医院妇产科,河北丰宁068350 [3]石家庄市中医院肛肠科,河北石家庄050021 [4]河北省中医院针灸科,河北石家庄050011 [5]河北北方学院研究生院,河北张家口075000

出　　处：《中国医药导报》2019年第27期134-137,142,共5页China Medical Herald

基　　金：河北省中医药管理局科研计划项目(2016095);河北省财政厅基金资助项目(361025)

摘　　要：目的研究调督熄风针法对肝阳上亢非杓型高血压病患者的影响。方法选取2017年10月~2018年10月于石家庄市中医院心三科就诊的符合入组标准的患者69例,最终完成临床研究的患者共60例,依照分层随机法分为治疗组和对照组,每组30例。对照组给予马来酸左旋氨氯地平片口服,治疗组给予马来酸左旋氨氯地平片口服,并行调督熄风针法针刺治疗,治疗4周。分别于治疗前后留取两组患者血液样本,测定一氧化氮(NO)、内皮素(ET)水平,同时记录两组患者治疗前后血压及血压下降率情况。结果与治疗前比较,两组夜间收缩压下降率显著升高(P<0.05);与对照组比较,治疗组夜间收缩压下降率显著增高(P<0.05)。治疗组非杓型转变为杓型血压率为56.7%(17/30),明显高于对照组[26.7%(8/30)],差异有统计学意义(P<0.05)。与治疗前比较,两组ET含量均降低,NO含量均升高,差异有统计学意义(P<0.05);与对照组比较,治疗组NO含量显著升高,ET含量显著降低(P<0.05)。结论调督熄风针法可以调整血压昼夜节律,同时对高血压病患者损伤的血管内皮功能有一定的改善作用。Objective To study the effect of Tiaodu Xifeng acupuncture in non-dipper hypertension patients with syndrome of upper hyperactivity of liver yang. Methods Sixty-nine patients met the inclusion criteria from October 2017 to October 2018 in the Three Cardiology Department of Shijiazhuang Hospital of Traditional Chinese Medicine were selected. A total of 60 patients completed the clinical study and they were divided into treatment group and control group by using stratified random method, with 30 cases in each group. The control group was given Levamlodipine Maleate Tablets, the treatment group was given Levamlodipine Maleate Tablets combined with Tiaodu Xifeng acupuncture, all the patients were treated for 4 weeks. Blood samples were taken from the two groups before and after treatment to measure the levels of nitric oxide (NO) and endothelin (ET), and the changes in blood pressure and blood pressure drop rate before and after treatment were recorded. Results Compared with before treatment, the decrease rate of nocturnal systolic blood pressure in the two groups was significantly increased (P < 0.05). Compared with the control group, the decrease rate of nocturnal systolic blood pressure in the treatment group was significantly increased (P < 0.05). The rate of non-dipperhypertension changing to dipper hypertension in the treatment group was 56.7%(17/30), which was higher than the control group [26.7%(8/30)], the difference was statistically significant (P < 0.05). Compared with before treatment, the content of ET in both groups decreased, the content of NO increased, and the differences were statistically significant (P < 0.05). Compared with the control group, the content of NO in the treatment group was significantly increased and the content of ET was significantly decreased (P < 0.05). Conclusion Tiaodu Xifeng acupuncture can adjust the circadian rhythm of blood pressure and improve the damaged vascular endothelial function in patients with hypertension.

关 键 词：调督熄风针法 肝阳上亢 高血压 血压昼夜节律 一氧化氮 内皮素 

分 类 号：R246.6[医药卫生—针灸推拿学]