18F-FDG PET/CT显像对胰腺癌与慢性肿块型胰腺炎的诊断价值  

Value of 18F-FDG PET/CT in Diagnosis of Pancreatic Cancer and Chronic Mass Type Pancreatitis

作　　者：张星[1] 马秀梅[2] ZHANG Xing;MA Xiu-mei(PETCT Center,Department of Nuclear Medicine,Yulin First Hospital,Yulin 719000,Shaanxi Province,China)

机构地区：[1]陕西省榆林市第一医院核医学科PETCT中心,陕西榆林719000 [2]陕西省榆林市第一医院影像科,陕西榆林719000

出　　处：《中国CT和MRI杂志》2019年第11期84-86,共3页Chinese Journal of CT and MRI

基　　金：陕西省卫生厅科研基金项目(编号:2015JM4029)

摘　　要：目的探究氟-代脱氧葡萄糖正电子发射型断层(18F-FDGPET/CT)显像对胰腺癌与慢性肿块型胰腺炎的诊断价值。方法回顾性分析30位健康查体者及72例胰腺病变患者的临床资料,其中慢性肿块型胰腺炎患者24例,胰腺癌患者48例,所有受试者均行18F-FDGPET/CT显像检查,其中44例在进行18F-FDGPET/CT显像检查前行增强CT扫描,比较18F-FDGPET/CT显像与增强CT的诊断效能。结果18F-FDGPET/CT显像诊断胰腺癌及慢性肿块型胰腺炎的灵敏度、特异度、准确度分别为93.75%、70.83%、86.11%,与临床诊断结果具有较高的一致性(Kappa=0.673);增强CT诊断灵敏度、特异度、准确度分别为70.45%、55.78%、70.45%;18F-FDGPET/CT对胰腺病变诊断效能显著优于增强CT扫描(P<0.05)。结论18F-FDGPET/CT显像对胰腺癌与慢性肿块型胰腺炎具有较高的诊断价值,可为临床诊断提供有效信息,诊断效能优于增强CT。Objective To investigate the value of positron emission tomography/computed tomography(PET/CT)using 18F-fluorodeoxyglucose(FDG)in diagnosis of pancreatic cancer and chronic mass type pancreatitis.Methods The clinical data of 30 healthy people receiving physical examination and 72 patients with pancreatic lesions were retrospectively analyzed.There were 24 patients with chronic mass type pancreatitis and 48 patients with pancreatic cancer.All subjects were examined by 18F-FDG PET/CT.44 patients underwent contrast-enhanced CT scan before 18F-FDG PET/CT examination.The diagnostic efficiency of 18F-FDG PET/CT and contrast-enhanced CT was compared.Results The sensitivity,specificity and accuracy of 18F-FDG PET/CT in the diagnosis of pancreatic cancer and chronic mass type pancreatitis(93.75%,70.83%and 86.11%)were highly consistent with clinical diagnosis(Kappa=0.673).The diagnostic sensitivity,specificity and accuracy of contrast-enhanced CT were 70.45%,55.78%and 70.45%,respectively.The diagnostic efficiency of 18F-FDG PET/CT was superior to that of contrast-enhanced CT in diagnosis of pancreatic lesions(P<0.05).Conclusion 18FFDG PET/CT is of high diagnostic value for pancreatic cancer and chronic mass type pancreatitis.It can provide useful information for clinical diagnosis and its diagnostic efficiency is better than contrast-enhanced CT.

关 键 词：氟-代脱氧葡萄糖正电子发射型断层显像 胰腺癌 慢性肿块型胰腺炎 增强CT 

分 类 号：R445.3[医药卫生—影像医学与核医学] R735.9[医药卫生—诊断学]