替吉奥胶囊在老年晚期胃癌治疗中的应用研究  

Application of Tiggio Capsule in the Treatment of Elderly Patients With Advanced Gastric Cancer

作　　者：颜劲[1] YAN Jin(Department of Oncology,Zhanjiang Central People's Hospital,Zhanjiang Guangdong 524000,China)

机构地区：[1]湛江中心人民医院肿瘤科

出　　处：《中国卫生标准管理》2019年第18期83-85,共3页China Health Standard Management

摘　　要：目的分析替吉奥胶囊在老年晚期胃癌治疗中的应用效果。方法选取我院于2017年1月—2019年1月收治的30例老年晚期胃癌患者,随机分为观察组与对照组,各15例,对照组给予FOLFOX化疗方案,观察组给予替吉奥胶囊治疗,比较组间患者治疗有效率与治疗前后肿瘤标志物水平变化情况。结果治疗前组间患者肿瘤标志物差异不存在统计学意义(P>0.05),治疗后观察组CEA、CA125、CA199低于对照组,差异具有统计学意义,P<0.05;观察组治疗总有效率高于对照组,对比组间数据(χ^2=3.968,P<0.05);观察组患者总发生率为26.7%,对照组患者总发生率为66.7%,经统计学分析比较,观察组不良反应发生率低于对照组,差异具有统计学意义,P<0.05。结论老年胃癌患者治疗过程中应用替吉奥胶囊效果显著。Objective To analyze the effect of Tiggio capsules in the treatment of advanced gastric cancer in the elderly.Methods Thirty patients with advanced gastric cancer admitted to our hospital from January 2017 to January 2019 were randomly divided into observation group and control group,15 cases in each group.The control group was given FOLFOX chemotherapy regimen.The observation group was given teggio.Capsule treatment,comparing the treatment efficiency of patients between groups and the changes of tumor marker levels before and after treatment.Results There was no significant difference in tumor markers between the two groups before treatment(P>0.05).After treatment,CEA,CA125 and CA199 were significantly lower in the observation group than in the control group,P<0.05.The effective rate was higher than that of the control group,and the data between the groups were compared(χ^2=3.968,P<0.05).The total incidence of adverse reactions in the observation group was 26.7%and 66.7%in the control group.Statistical analysis showed that the incidence of adverse reactions in the observation group was significantly lower than that in the control group,and the difference was P<0.05,indicating that there was statistical significance.Conclusion The application of tiggio capsules in the treatment of elderly patients with gastric cancer has significant clinical significance.

关 键 词：替吉奥胶囊 老年 肿瘤标志物 晚期 胃癌 治疗 

分 类 号：R975[医药卫生—药品]