心脏瓣膜置换术治疗巨大左心室心脏瓣膜病的临床效果分析  

Clinical Analysis of Heart Valve Replacement for Treatment of Giant Left Ventricular Valvular Heart Disease

作　　者：高开柱 李庆国[1] 李小波 耿直[1] 赵向东[1] 李娟[1] GAO Kai-zhu;LI Qing-guo;LI Xiao-bo;GENG Zhi;ZHAO Xiang-dong;LI Juan(Cardiovascular Center,Second Affiliated Hospital of Nanjing Medical University,Nanjing,Jiangsu Province,210000 China)

机构地区：[1]南京医科大学第二附属医院心血管病中心

出　　处：《中外医疗》2019年第26期82-84,129,共4页China & Foreign Medical Treatment

摘　　要：目的分析巨大左心室心脏瓣膜病患者采用心脏瓣膜置换术的临床治疗效果。方法随机选择该院在2016年2月—2018年8月期间收治的25例巨大左心室心脏瓣膜病患者,均采用心脏辨膜置换术进行治疗,观察患者的临床效果。结果患者术前抑郁评分(11.43±6.12)分、焦虑评分(16.85±4.84)分和生活质量评分(76.14±8.23)分和术后3个月的抑郁评分(8.35±4.44)分、焦虑评分(11.48±4.21)分和生活质量评分(80.84±8.10)分,组间差异有统计学意义(t=2.0367、4.1856、2.0350,P=0.0472、0.0001、0.0474<0.05)。患者术后1周、3个月的LVEDD(63.32±9.84)mm、(57.65±9.12)mm和LVESD(48.64±10.12)mm、(40.12±11.20)mm呈下降趋势,与术前对比组间差异有统计学意义(t=6.5145,9.0455,4.5947、7.2274,P=0.0000、0.0000、0.0000、0.0000<0.05)。结论心脏瓣膜置换术治疗巨大左心室心脏瓣膜病患者的临床效果显著,可以有效改善患者心功能情况,降低患者死亡率,提高生活质量,可以在临床治疗中推广使用。Objective To analyze the clinical therapeutic effect of heart valve replacement in patients with massive left ventricular valvular heart disease.Methods Twenty-five patients with giant left ventricular valvular heart disease who were admitted to our hospital from February 2016 to August 2018 were randomly selected for treatment with cardiac discectomy.The clinical effects of the patients were observed.Results The preoperative depression score(11.43±6.12)points,anxiety score(16.85±4.84)points and quality of life score(76.14±8.23)points,and postoperative depression score(8.35±4.44)points and anxiety score(11.48±4.21)points and quality of life scores(80.84±8.10)points,with academic significance(t=2.036 7,4.185 6,2.035 0,P=0.047 2,0.000 1,0.047 4<0.05).Patients with LVEDD(63.32±9.84)mm,(57.65±9.12)mm,and LVESD(48.64±10.12)mm,(40.12±11.20)mm showed a downward trend at 1 week and 3 months after surgery,compared with preoperative,the difference between the groups was statistically significant(t=6.514 5,9.045 5,4.594 7,7.227 4,P=0.000 0,0.000 0,0.000 0,0.000 0<0.05).Conclusion The clinical effect of heart valve replacement in the treatment of patients with giant left ventricular valvular heart disease is significant,which can effectively improve the heart function of patients,reduce the mortality rate of patients,improve the quality of life,and can be promoted in clinical treatment.

关 键 词：心脏瓣膜置换术 巨大左心室 心脏瓣膜病 

分 类 号：R654[医药卫生—外科学]