不同手术方式治疗子宫肌瘤后卵巢功能及性生活质量研究  

Effects of different surgical methods on ovarian function and sexual life quality of patients with hysteromyoma

作　　者：张瑜 李萍[1] 刘灵霞[1] 王亚宁[1] 陈琼[1] 李雪峰[1] ZHANG Yu;LI Ping;LIU Lingxia;WANG Yaning;CHEN Qiong;LI Xuefeng(Department of Gynaecology,People′s Hospital of Banan District,Chongqing 401320,China)

机构地区：[1]重庆市巴南区人民医院妇科

出　　处：《检验医学与临床》2019年第20期2928-2932,共5页Laboratory Medicine and Clinic

基　　金：重庆市巴南区科委面上项目（2015-31-49）

摘　　要：目的探讨3种手术方式对子宫肌瘤患者术后卵巢功能及性生活质量的影响。方法选取2015年5月1日至2017年4月30日因子宫肌瘤在该院手术治疗的绝经前患者作为研究对象,根据不同手术方式分为3组:子宫肌瘤切除术组(A组)、次全子宫切除术组(B组)、全子宫切除术组(C组),对术前、术后6个月、术后12个月女性激素3项[雌二醇(E2)、卵泡刺激素(FSH)、黄体生成素(LH)]水平进行检测,并用女性性功能指数(FSFI)量表对性生活进行评估。结果A组术后6个月、术后12个月与术前比较,激素3项检测水平差异均无统计学意义(P>0.05)。B组及C组术后6个月、术后12个月与术前比较,激素3项检测水平变化差异均有统计学意义(P<0.05)。术前3组患者性生活质量评分差异无统计学意义(P>0.05);术后6个月、术后12个月分别与术前比较,FSFI量表评分均升高,差异均有统计学意义(P<0.05);FSFI量表评分:A组>B组>C组,差异均有统计学意义(P<0.05)。结论3种手术方式中子宫肌瘤切除在保护卵巢功能及提高性生活质量方面效果更佳。Objective To explore the effects of three kinds of operation(myomectomy,subtotal hysterectomy and total hysterectomy)on the ovarian function and sexual life quality of patients with hysteromyoma.Methods The premenopausal patients with hysteromyoma who were treated in the People′s Hospital of Banan District from May 1,2015 to April 30,2017 were divided into three groups according to different operation methods:group A treated with myomectomy,group B treated with subtotal hysterectomy and group C treated with hysterectomy.Three female hormones[(estradiol)E 2,(follicle stimulating hormone)FSH and(luteinizing hormone)LH]were measured respectively before treatment,6 months and 12 months after the operation to evaluate ovarian function,and the female sexual function index(FSFI)was used to evaluate the sex life quality.Results In group A,the levels of the three hormones showed no significant differences at 6 months and 12 months after operation compared with before operation(P>0.05).While there were significant differences at 6 months and 12 months after operation compared with before operation in group B and group C(P<0.05).Before treatment,there were no statistical significance between the three groups in the scores of sex life quality(P>0.05).At 6 and 12 months after operation,the score of FSFI were significantly higher when compared with those before operation(P<0.05).And the score of FSFI of group A was significantly higher than that of group B(P<0.05),at the same time,the score of group B was significantly higher than that of group C(P<0.05).Conclusion Among the three treatments for hysteromyoma,myomectomy is more effective in protecting ovarian function and improving sex life quality.

关 键 词：子宫肌瘤 子宫肌瘤切除术 次全子宫切除术 全子宫切除术 卵巢功能 

分 类 号：R713.33[医药卫生—妇产科学]