Design, Synthesis and Insecticidal Activities of Novel 5-Alkoxyfuran-5(H)-one Derivatives  

作　　者：WANG Xianhao LI Jianguo WANG Guangjian HAN Xianzheng LI Dongmei TIAN Zhongzhen 

机构地区：[1]Shandong Provincial Key Laboratory of Fluorine Chemistry and Chemical Materials,School of Chemistry and Chemical Engineering,University of Jinan,Jinan 266042,P.R.China [2]Research and Development Center,Hailir Pesticides and Chemicals Group Co.,Ltd.,Qingdao 266109,P.R.China [3]State Key Laboratory Base for Eco-Chemical Engineering in College of Chemical Engineering,Qingdao University of Science and Technology,Qingdao 266042,P.R.China

出　　处：《Chemical Research in Chinese Universities》2019年第5期799-805,共7页高等学校化学研究（英文版）

基　　金：Supported by the Natural Science Foundation of Shandong Province,China(No.ZR2018MB013);the National Natural Science Foundation of China(No.21501066);the Key Research and Development Program of Shandong Province,China (No.2016GGX 107006).

摘　　要：A series of novel 5?alkoxyfuran-2(5H)-one derivatives was synthesized, and characterized by 1H NMR, 13C NMR and HRMS. Biological activities of all the title compounds were evaluated systematically. Preliminary bioassays indicated that most of the compounds exhibited moderate insecticidal activities against Aphis craccivora and Nilaparvata lugens at 100 mg/L. Compounds 4h and 4w exhibited 100% mortality rate against Aphis craccivora at 100 mg/L, and compound 4h exhibited good mortality rate against Aphis craccivora and Nilaparvata lugens (60% and 75%, respectively) even at 4 mg/L. The results demonstrated the impact of various chemical groups on insecticidal activities and provided a potential clue for further exploring novel high-effective broad-spectrum insecticides.

关 键 词：BUTENOLIDE DERIVATIVE Flupyradifurone NEONICOTINOID INSECTICIDAL activity 

分 类 号：O6[理学—化学]