电子顺磁共振技术在药学实验中的应用探索  

Application of electron paramagnetic resonance in pharmaceutical experiments

作　　者：赵淑锐 郑美青 吴英婷 王耀楠 ZHAO Shurui;ZHENG Meiqing;WU Yingting;WANG Yaonan(Central Laboratory, Capital Medical University, Beijing 100069, China)

机构地区：[1]首都医科大学中心实验室

出　　处：《实验技术与管理》2019年第10期201-203,共3页Experimental Technology and Management

摘　　要：电子顺磁共振(ESR)技术是检测单电子的唯一的直接分析方法,该文将这种方法应用到了药学专业实验教学中.通过NO自由基的清除实验教学,不仅使学生直接接触了现代大型电子顺磁共振仪,熟悉了NO自由基的产生、捕捉机理及清除方法,还培养了学生的科研思维,形成了药学专业人才培养特色,提高了学生的综合实验技能.Electron paramagnetic resonance (ESR) is the only direct analytical method for single electron detection, and this method has been applied to the experimental teaching of Pharmacy specialty. Through the experimental teaching of NO free radical scavenging, students are not only directly exposed to modern large-scale electronic paramagnetic resonance instruments and familiar with the generation, capture mechanism and scavenging method of NO free radical, but also train their scientific research thinking, form the characteristics of cultivating pharmaceutical talents and improve their comprehensive experimental skills.

关 键 词：药物化学实验 电子顺磁共振仪 一氧化氮自由基 

分 类 号：R91[医药卫生—药学] G642.423[文化科学—高等教育学]