平喘止咳汤在慢阻肺急性发作期患者中的应用效果及对呼吸力学状态的影响研究  

Study on Application Efficacy of Pingchuan Zhike Decoction in Patients with Chronic Obstructive Pulmonary Disease During Acute Episode and Its Effects on Respiratory Mechanics State

作　　者：黎晓莉[1] 何亦龙[1] 杨熙芮 唐燕[1] Li Xiaoli;He Yilong;Yang Xirui;Tang Yan(Department of Respiratory Medicine,Guangyuan Second People′s Hospital in Sichuan Province,Guangyuan 628017,China)

机构地区：[1]四川省广元市第二人民医院呼吸内科

出　　处：《世界中医药》2019年第9期2412-2415,共4页World Chinese Medicine

基　　金：四川省卫生厅科研项目(170967)

摘　　要：目的:研究平喘止咳汤在慢阻肺急性发作期患者中的应用效果及对呼吸力学状态的影响。方法:选取2017年1月至2018年2月广元市第二人民医院收治的慢阻肺急性发作期患者90例作为研究对象,随机分为对照组和观察组,每组45例。对照组进行慢阻肺急性发作期常规西医治疗,观察组在对照组基础上加用平喘止咳汤。观察2组的临床治疗效果(临床总有效率、中医证候积分及肺功能参数),评估2组的呼吸力学状态(呼吸阻抗、胸肺顺应性)变化情况。结果:观察组的临床总有效率(86.67%及95.56%)显著高于对照组(64.44%及80.00%)(P<0.05);治疗后观察组的中医证候积分及呼吸阻抗均低于对照组(P<0.05);胸肺顺应性及肺功能参数高于对照组(P<0.05)。结论:平喘止咳汤在慢阻肺急性发作期患者中的应用效果较好,且对呼吸力学状态改善作用积极,因此在慢阻肺急性发作期患者中的应用价值较高。Objective: To study application efficacy of Pingchuan Zhike Decoction in patients with chronic obstructive pulmonary disease(COPD)during acute episode and its effects on respiratory mechanics state. Methods: A total of 90 patients with COPD during acute episode admitted in the Guangyuan Second People′s Hospital from January 2017 to February 2018 were chosen for the study,and they were randomly divided into control group and observation group,with 45 cases in each group.The control group was treated with routine western medicine for COPD during acute episode,while the observation group was treated with Pingchuan Zhike Decoction on the basis of the treatment in the control group.Then the clinical efficacy [totalclinical effective rate,syndrome scores of tratidional Chinese medicine(TCM)and pulmonary function parameters] in the 2 groups were observed.The changes of respiratory mechanics state(respiratory impedance,thoracic and lung compliance)in the 2 groups were evaluated. Results: The total clinical effective rates(86.67% and 95.56%)in the observation group were higher than 64.44% and 80.00%% in the control group( P <0.05);the TCM syndrome scores and respiratory impedance in the observation group after the treatment were all lower than those in the control group( P <0.05);the thoracic and lung compliance amd the pulmonary function parameters were higher than those in the control group( P <0.05). Conclusion: The application efficacy of Pingchuan Zhike Decoction in the patients with COPD during acute episode is good,and it plays an active improvement role in the respiratory mechanics state,so its application value in the patients with COPD during acute episode.

关 键 词：平喘止咳汤 慢阻肺急性发作期 应用效果 呼吸力学状态 中医证候积分 肺功能参数 呼吸阻抗 胸肺顺应性 

分 类 号：R256.11[医药卫生—中医内科学]