松香树脂酸及其衍生物的分子自组装研究进展  

The Research Progress in Molecular Self-assembly of Rosin Resin Acids and Their Derivatives

作　　者：韩春蕊 周若男 韩冰 田超 徐鹏飞 宋先亮 HAN Chunrui;ZHOU Ruonan;HAN Bing;TIAN Chao;XU Pengfei;SONG Xianliang(College of Materials Science and Technology,Beijing Forestry University,MOE Engineering Research Center of Forestry Biomass Materials and Bioenergy, Beijing 100083, China;Key Lab of Biomass Energy and Material,Jiangsu Province, Nanjing 210042, China)

机构地区：[1]北京林业大学材料科学与技术学院,林业生物质材料与能源教育部工程研究中心,北京100083 [2]江苏省生物质能源与材料重点实验室,江苏南京210042

出　　处：《林产化学与工业》2019年第5期1-10,共10页Chemistry and Industry of Forest Products

基　　金：北京林业大学国家级大学生创新训练项目(G201910022054);江苏省生物质能源与材料重点实验室开放基金项目(JSBEM201911)

摘　　要：松香树脂酸具有羧基、双键和苯环富电中心等多修饰位点,通过化学改性可得到具有丰富亲水基团的各种松香树脂酸衍生物;松香树脂酸及其衍生物分子中既含有独特的刚性三环萜烯疏水骨架基团和手性结构,又含有羧酸和新引入的各种亲水基团,使其在溶液中呈现出特殊的分子自组装性能,而赋予自组装聚集体高表面活性、智能响应和靶向载药等多种功能性。根据化合物的结构特点,对松香树脂酸及其衍生物的小分子自组装、超分子自组装、高分子自组装以及有机-无机杂化分子自组装进行综述;分析自组装聚集行为,归纳自组装特点,并总结其在表面活性、智能响应、载药和无机纳米材料修饰等领域的应用。最后,对松香树脂酸及其衍生物的自组装功能性材料的发展进行展望。There are many modification sites, such as carboxyl, double bond and benzene ring electric-rich center in the structure of rosin acids. Rosin based derivatives with abundant hydrophilic groups have been obtained by chemical modification. Rosin acids and their derivatives show special self-assembly ability in solutions because they are composed of carboxylic acid, new hydrophilic groups and the unique hydrophobic skeleton, chiral structure of rigid tricyclic terpenes. As a result, rosin and rosin-based derivatives have many functions including high surface activity, smart responsiveness and targeted drug delivery by self-assembly of molecules. According to the structural characteristics of the compounds, the self-assembly of resin acids and their derivatives in small molecules, supramolecules, macromolecules and organic-inorganic hybrid molecules is reviewed. The self-assembly aggregates are analyzed. The self-assembly behaviors and characteristics of resin acids and their derivatives are summarized. The applications in surface activity, smart responsiveness, drug delivery and modification of inorganic nanomaterials are overviewed. Finally, the developments on functional materials and self-assembled aggregates of resin acids and their derivatives are prospected.

关 键 词：松香 刚性 萜烯 自组装 靶向载药 杂化材料 

分 类 号：TQ35[化学工程]