妊娠期糖尿病合并亚临床甲减对妊娠结局的影响  

Effect of Gestational Diabetes Mellitus With Subclinical Hypothyroidism on Pregnancy Outcome

作　　者：杨慧[1] YANG Hui(Department of Obstetrics and Gynecology, Yangzhou Maternaland Child Health Hospital, Yangzhou Jiangsu 225001, China)

机构地区：[1]江苏省扬州市妇幼保健院妇产科

出　　处：《中国继续医学教育》2019年第30期108-110,共3页China Continuing Medical Education

摘　　要：目的对妊娠期糖尿病合并亚临床甲状腺功能减退在妊娠结局方面的影响进行探讨。方法选取2018 年1 月—2018 年12 月间收治的孕妇共68 例,将其依据孕妇自身情况分组,每组17 例孕妇,分别妊娠期糖尿病孕妇、合并亚临床甲减孕妇、妊娠期糖尿病并亚临床甲减孕妇和正常孕妇,依次设定为糖尿病组、亚甲减组、合并组和对照组,对4 组不同情况孕妇的妊娠结局进行探讨。结果糖尿病组妊娠并发症发生率为11.76%,亚甲减组妊娠并发症发生率为23.52%,合并组妊娠并发症发生率为35.28%,对照组妊娠并发症发生率为5.88%,数据比较,合并组妊娠并发症发生率与其他三组相比,均偏高(P < 0.05)。妊娠结局方面:合并组的流产率23.53%、早产率17.65%、剖宫产率29.41%,分别高于其他三组(P < 0.05)。而合并组的顺产率29.41%分别低于其他三组(P < 0.05)。结论妊娠期糖尿病并亚临床甲减对妊娠结局有直接的影响,降低了顺产率,而且增加了剖宫产率、流产率及早产率,因此,临床医师要提高警惕,及时发现及时治疗,确保新生儿顺利出生。Objective To investigate the effect of gestational diabetes mellitus (GDM) combined with subclinical hypothyroidism on pregnancy outcome. Methods A total of 68 pregnant women admitted between January 2018 and December 2018 were selected and grouped according to their own conditions. 17 pregnant women in each group were divided into four groups: pregnant women with gestational diabetes mellitus, pregnant women with subclinical hypothyroidism, pregnant women with gestational diabetes mellitus and subclinical hypothyroidism and normal pregnant women. Pregnancy outcome was discussed. Results The incidence of pregnancy complications was 11.76% in diabetes mellitus group, 23.52% in hypothyroidism group, 35.28% in combined group and 5.88% in control group. Compared with other three groups, the incidence of pregnancy complications in combined group was higher (P < 0.05). In terms of pregnancy outcome, the abortion rate, premature delivery rate and cesarean section rate in the combined group were 23.53%, 17.65% and 29.41%, respectively, higher than those in the other three groups (P < 0.05). The spontaneous rate of 29.41% in the combined group was lower than that in the other three groups (P < 0.05). Conclusion Subclinical addition and subtraction of gestational diabetes mellitus has a direct impact on pregnancy outcomes, reduces the rate of spontaneous birth, and increases the rate of cesarean section, abortion and causes. Therefore, clinicians should be vigilant, timely detection and treatment to ensure the smooth birth of newborns.

关 键 词：妊娠期 糖尿病 亚临床甲减 妊娠结局 剖宫产 顺产 流产 

分 类 号：R714[医药卫生—妇产科学]