我院急诊超说明书用药情况调查分析  

Investigation and analysis of off-label drug uses of the emergency department in our hospital

作　　者：王旭[1] Wang Xu(The Second Hospital of Tianjin Medical University, Tianjin 300201)

机构地区：[1]天津医科大学第二医院

出　　处：《天津药学》2019年第5期36-39,共4页Tianjin Pharmacy

摘　　要：目的:对本院急诊超说明书用药情况进行分析,为临床合理用药和法律法规制定提供参考。方法:分层随机抽取本院2018年1—12月急诊处方,对超说明书用药发生率、超说明书用药类型、年龄段和药物种类进行统计分析。结果:本院急诊超说明书用药发生率按处方数和用药记录数计分别为25.50%和12.78%。超说明书用药类型包括超用法用量(53.36%)、超适应人群(21.78%)、超适应症(18.57%)和超给药途径(6.29%)。其中发生率排前两位的年龄段为婴幼儿和儿童;发生率居前两位的药物种类为抗感染药和呼吸系统用药。结论:本院急诊超说明书用药现象基本处于合理范围,仍需从多方面对超说明书用药现象进行规范。Objective: To provide reference for clinical rational drug use and legal regulations, we investigated the off-label drug uses in emergency department of our hospital. Methods: The prescriptions were randomly selected from emergency department of our hospital during January to December 2018.The prescriptions of off-label drug use were picked out and statistically analyzed in the type of off-label drug use, the relationship of different age groups with various drugs. Results: According to the number of prescriptions and medication records, the incidences of off-label drug use were 25.50% and 12.78%, respectively. The four reasons for off-label drug use were over usage and dosage (53.36%), over applicable people (21.78%), over indications ( 18.57%) and over contraindications (6.29%). The top two groups of off-label drug use were infants and children. Main drugs in off-label use involved anti-infective medicines and respiratory system medicines. Conclusion: The phenomenon of off-label drug use in the emergency department of our hospital is basically in a reasonable range. It is necessary to regulate the phenomenon of off-label drug use in many aspects.

关 键 词：超说明书用药 急诊 合理用药 

分 类 号：R969.3[医药卫生—药理学]