大隐静脉高位结扎及腔内激光联合泡沫硬化剂腔内注射微创手术治疗下肢静脉曲张的临床效果  

Clinical Effect of High Ligation of the Great Saphenous Vein and Intracavitary Laser Combined with Intracavitary Injection of Sclerosing Foam in the Treatment of Varicose Veins of Lower Extremity

作　　者：巫志华[1] 邱耿锋[1] 张贵荣[1] WU Zhihua;QIU Gengfeng;ZHANG Guirong(Longyan Second Hospital, Longyan 364000, China)

机构地区：[1]龙岩市第二医院

出　　处：《中外医学研究》2019年第28期12-14,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨大隐静脉高位结扎及腔内激光联合泡沫硬化剂腔内注射治疗下肢静脉曲张的临床效果。方法:选择2017年1月-2018年12月笔者所在医院接诊的下肢静脉曲张患者298例,按照随机数字表法分为对照组(n=149)和观察组(n=149)。对照组采用大隐静脉高位结扎联合腔内激光治疗,观察组在对照组治疗基础上实施泡沫硬化剂腔内注射,对比两组治疗效果。结果:观察组手术时间长于对照组,住院时间、医疗费用均少于对照组(t=-11.317、9.285、9.109,P<0.05)。两组失血量、切口数量对比,差异均无统计学意义(t=1.394、1.525,P>0.05)。术后1周,两组凝血功能和炎性因子均较术前改善(P<0.05);观察组纤维蛋白原、白细胞介素-2、白细胞介素-10均低于对照组,凝血酶原时间长于对照组,差异均有统计学意义(t=12.682、-4.937、5.591、9.439,P<0.05)。观察组术后1个月治疗效果优于对照组(Z=3.781,P<0.05)。结论:大隐静脉高位结扎及腔内激光联合泡沫硬化剂腔内注射治疗下肢静脉曲张,可以提升治疗效果,改善术后凝血功能及炎性反应情况,促进患者恢复。Objective: To investigate the clinical effect of high ligation of the great saphenous vein and intracavitary laser combined with intracavitary injection of sclerosing foam in the treatment of varicose veins of lower extremity. Method: A total of 298 patients with varicose veins of lower extremity who were admitted to our hospital from January 2017 to December 2018 were selected. According to the method of random number, patients were divided into the control group (n=149) and the observation group (n=149). The control group was treated with high ligation of the great saphenous vein and intracavitary laser treatment. The observation group was treated with intracavitary injection of sclerosing foam on the basis of the control group. The treatment effects of the two groups were compared. Result: The operation time of the observation group was longer than that of the control group, and the length of hospital stay and the medical expenses were less than those of the control group (t=-11.317, 9.285, 9.109, P<0.05). The blood loss, the number of incisions were compared between the two groups, and the differences were not statistically significant (t=1.394, 1.525, P>0.05). One week after the operation, coagulation function and inflammatory factors of the two groups were improved compared with those before operation (P<0.05). The fibrinogen, interleukin-2 and interleukin-10 in the observation group were lower than those of the control group, and the prothrombin time was longer than that of the control group (t=12.682,-4.937, 5.591, 9.439, P<0.05). The therapeutic effect of the observation group was better than that of the control group one month after operation (Z=3.781, P<0.05). Conclusion: High ligation of the great saphenous vein and intracavitary laser combined with intracavitary injection of sclerosing foam for the treatment of varicose veins of lower extremity can improve treatment, improve postoperative coagulation and inflammatory response, and promote recovery of patients.

关 键 词：大隐静脉高位结扎 泡沫硬化剂 微创手术 下肢静脉曲张 

分 类 号：R654.4[医药卫生—外科学]