右美托咪定和丙泊酚在硬膜外麻醉手术中的应用对比  

Comparison of the Application of Dextromethidine and Propofol in Epidural Anesthesia

作　　者：胡荣清 HU Rongqing(Maternal and Child Health Hospital of Fang County,Fang County 442100,China)

机构地区：[1]房县妇幼保健院

出　　处：《中外医学研究》2019年第27期160-162,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:对比右美托咪定与丙泊酚在硬膜外麻醉手术中的应用价值。方法:选取笔者所在医院2018年1-12月接收的采取妇科手术治疗的70例患者为研究对象,随机分为两组,A组(n=35)采取右美托咪定麻醉,B组(n=35)采用丙泊酚麻醉,统计各组不同时间平均动脉压、心率、Ramsay镇静评分及不良反应发生率。结果:两组麻醉前及术后60 min平均动脉压、Ramsay镇静评分及心率对比差异无统计学意义(P>0.05);A组麻醉后15 min、术后15 min及手术完毕各项指标均优于B组,差异均有统计学意义(P<0.05)。A组不良反应发生率(5.71%)低于B组(25.71%),差异有统计学意义(P<0.05)。结论:右美托咪定在硬膜外麻醉手术中应用效果较丙泊酚更优,不仅具有良好的镇静、镇痛效果,同时有助于避免其他反应的发生。Objective:To compare the value of Dexmedetomidine and Propofol in epidural anesthesia.Method:Seventy patients who underwent gynecological surgery in our hospital from January 2018 to December 2018 were randomly divided into two groups.The group A(n=35) was anesthetized with Dexmedetomidine,and the group B(n=35) was anesthetized with Propofol.The mean arterial pressures,heart rates,Ramsay sedation scores and incidences of adverse reactions at different time were counted.Result:There was no significant difference in mean arterial pressure,Ramsay sedation score and heart rate in both groups before anesthesia and 60 min after operation(P>0.05).The indexes of 15 min after anesthesia,15 min in operation and at the end of the operation in group A were better than those in group B,the differences were statistically significant(P<0.05).The adverse reaction of group A(5.71%) was lower than 25.71% of group B(P<0.05).Conclusion:Dexmedetomidine is more effective than Propofol in epidural anesthesia.It not only has good sedative and analgesic effects,but also helps to avoid other reactions.

关 键 词：硬膜外麻醉手术 丙泊酚 右美托咪定 RAMSAY镇静评分 

分 类 号：R614[医药卫生—麻醉学]