1例由输入性疟疾感染者引起输血疟疾的调查  

Epidemiological investigation of blood transfusion-induced malaria caused by an imported case with Plasmodium falciparum infection

作　　者：黄文明[1] 陈剑峰[1] 张翔[1] 何义林[1] HUANG Wen-Ming;CHEN Jian-Feng;ZHANG Xiang;HE Yi-Lin(Taizhou Municipal Center for Disease Control and Prevention,Jiangsu Province,Taizhou 225300,China)

机构地区：[1]江苏省泰州市疾病预防控制中心

出　　处：《中国血吸虫病防治杂志》2019年第4期439-440,F0003,共3页Chinese Journal of Schistosomiasis Control

摘　　要：目的对泰州市1例因输血感染恶性疟的病例进行分析,为疟疾防控提供科学依据。方法对1例恶性疟患者开展流行病学追踪调查,通过实验室方法对供血者血样进行检测,以明确感染来源。结果 1名64岁肾病住院患者的血液标本镜检查见疟原虫,确诊为恶性疟。经流行病学调查,患者除接受过输血外,无非洲和东南亚等恶性疟流行区旅行史;住院期间曾接受14次输血治疗,对23份供血者血样进行检测,发现1名印度尼西亚籍留学生留存血样PCR检测呈恶性疟原虫阳性,流行病学调查发现该供血者曾有疟疾感染史。结论该患者为输血感染恶性疟病例,应加强对献血者的疟疾筛查,以预防输血传播疟疾的发生。Objective To analyze a case infected with Plasmodium falciparum due to blood transfusion in Taizhou City, so as to provide scientific evidence for malaria control. Methods The epidemiological investigation of a case with P. falciparum malaria was conducted, and the blood donors’ blood samples were collected and detected in laboratory to identify the origin of the infection. Results Microscopy detected Plasmodium in the blood samples from a 64-year-old male inpatient with nephropathy,and P. falciparum malaria was diagnosed. The case had no history of travel to Africa or Southeast Asia except blood transfusion,and he had received blood transfusion 14 times during his hospital stay. Detection of blood donors’ blood samples showed P. falciparum in the archived blood samples from an Indonesian student studying in China, as revealed by PCR assay, and the student was found to have a history of malaria. Conclusions The patient was confirmed to be a case with P. falciparum malaria due to blood transfusion. Screening of malaria should be intensified in blood donors to prevent the development of malaria transmitted by blood transfusion.

关 键 词：恶性疟 输血 流行病学调查 泰州市 

分 类 号：R531.3[医药卫生—内科学]