血清淀粉样蛋白A水平与冠状动脉粥样硬化的研究进展  

The research progress of serum amyloid A level and coronary atherosclerosis

作　　者：常程 潘一龙[1] 杜洪姣 李晓东[1] CHANG Cheng;PAN Yi-long;DU Hong-jiao;LI Xiao-dong(Department of Cardiovascular Medicine,Shengjing Hospital Affiliated to China Medical University,Shenyang 110022,China)

机构地区：[1]中国医科大学附属盛京医院第一心血管内科,辽宁省沈阳市110022

出　　处：《中国心血管病研究》2019年第10期942-945,共4页Chinese Journal of Cardiovascular Research

基　　金：“十二五”国家科技支撑计划(2014BAL11B04).

摘　　要：冠状动脉粥样硬化性心脏病简称“冠心病”,是一种危害健康的主要疾病.所以早期识别相关生物学标志物是做到对疾病早诊断、早治疗的关键.血清淀粉样蛋白A(SAA)是一种由肝脏合成的急性期蛋白,属于炎性标志物.近年来大量研究发现SAA与冠心病的发生发展存在明显的关联性.因此,本文就近年来关于SAA与冠心病的相关性的研究成果作进一步综述.Coronary atherosclerotic heart disease, short for "coronary heart disease", is a major disease endangering the health of global citizens. Therefore, the early identification of relevant biomarkers is the key to diagnosis and treatment the disease earlier. Serum amyloid A (SAA) is an acute phase protein synthesized by the liver, which is an inflammatory marker. In recent years, a great deal of studies have found that SAA is significantly related to the occurrence and development of coronary heart disease. Therefore, this paper further reviews the research results in recent years in the relationship between SAA and coronary heart disease.

关 键 词：血清淀粉样蛋白A 动脉粥样硬化 冠状动脉疾病 炎症 

分 类 号：R541.4[医药卫生—心血管疾病]