158例糖尿病足流行病学及相关危险因素分析  

Epidemiology of 158 cases of diabetic foot and analysis of related risk factors

作　　者：任明容 汪义[1] 张勇[1] 苏静[1] Ren Mingrong;Wang Yi;Zhang Yong;Su Jing(Mianzhu Peoples Hospital,Mianzhu 618200,China)

机构地区：[1]四川省绵竹市人民医院

出　　处：《临床医学》2019年第10期4-6,共3页Clinical Medicine

摘　　要：目的探讨158例糖尿病足流行病学及相关危险因素。方法选取2012年1月至2018年12月糖尿病足患者158例作为观察组,另选择150例单纯糖尿病患者作为对照组,回顾性分析所有患者的临床资料。结果病程范围在11~20年的糖尿病患者发生糖尿病足的概率最高,为80例(50.6%,80/158);小学及初中文化程度的占比最高,分别为47例(29.7%,47/158)、38例(24.1%,38/158);占比最高的为WagnerⅡ级88例(55.7%,88/158);且随着Wagner分级升高,患者的住院时间及截肢率更高,差异有统计学意义(P<0.05)。单因素分析发现,观察组的糖尿病病程较对照组更长,血清糖化血红蛋白(HbA1c)值更高,纤维蛋白原(FIB)水平升高,白蛋白水平降低,踝肱指数(ABI)及经皮氧分压监测(TcPO2)降低,差异有统计学意义(P<0.05)。Logistic回归分析结果提示,糖尿病病程、血清HbA1c、FIB、白蛋白、ABI及TcPO2是影响糖尿病足发生的独立风险因素(P<0.05)。结论糖尿病足患者大部分文化程度较低,且多为高龄者;对风险患者加强糖尿病相关知识的宣教,严格控制患者的血糖水平,并积极维持患者的血纤维蛋白原、血脂及血压正常,同时积极给予患者治疗相关慢性合并症,可降低临床中糖尿病足的发生率。Objective To investigate the epidemiology and related risk factors of 158 cases of diabetic foot. Methods A total of 158 patients with diabetic foot from January 2012 to December 2018 were selected as observation group. Another 150 patients with simple diabetes mellitus were selected as control group. The clinical data of all patients were analyzed retrospectively. Results The incidence of diabetic foot in diabetic patients with a course of 11 to 20 years was the highest, accounting for 80 cases(50.6%,80/158). Primary school and junior high school had the highest proportion of cultural level, 47 cases(29.7%,47/158) and 38 cases(24.1%,38/158), respectively. The highest proportion was Wagner II in 88 cases(55.7%,88/158). With the increase of Wagner grade, the hospitalization time and amputation rate of patients were higher, the differences were significant(P< 0.05). Univariate analysis showed that the duration of diabetes in the observation group was longer than that in the control group, the value of glycosylated hemoglobin(HbA1 c) was higher, the level of fibrinogen(FIB) was higher, the level of albumin was lower, the ankle brachial index(ABI) and transcutaneous oxygen partial pressure monitoring(TcPO2) were lower, the differences were significant(P<0.05). Logistic regression analysis indicated that, the duration of diabetes mellitus, serun HbA1 c, FIB, albumin, ABI and transcutaneous partial oxygen pressure monitoring(TcPO2) were the independent risk factors for diabetic foot(P<0.05). Conclusions Most of the patients with diabetic foot have low educational level and are mostly elderly. Strengthening the education of diabetes-related knowledge for risk patients, strictly controlling the blood glucose level of patients, and actively maintaining the patients’ fibrinogen, blood lipid and blood pressure, while actively giving patients treatment for related chronic complications, can reduce the incidence of diabetic foot in clinical practice.

关 键 词：糖尿病足 危险因素 流行病学 糖尿病 

分 类 号：R587.2[医药卫生—内分泌]