吸烟、超重及肥胖对女性早发冠心病影响  

Smoking,overweight and obesity affect the early onset of coronary heart disease in women

作　　者：孙莹 韩雅玲 李毅 李治国 关绍义 马颖艳 SUN Ying;HAN Ya-ling;LI Yi;LI Zhi-guo;GUAN Shao-yi;MA Ying-yan(Department of Cardiovascular,General Hospital of Northern Theater Command,Shenyang 110016,China)

机构地区：[1]北部战区总医院心血管内科

出　　处：《临床军医杂志》2019年第10期1041-1043,F0002,共4页Clinical Journal of Medical Officers

基　　金：国家十二五科技支撑计划课题(2011BAI11B07)

摘　　要：目的探讨吸烟、超重及肥胖对女性早发冠心病的影响。方法选取自2012年1月至2014年3月因胸闷、胸痛入院的3 779例女性冠心病患者为研究对象,根据患者吸烟与否将患者分为吸烟组(n=318)与非吸烟组(n=3 461);根据患者体质量指数将患者(排除2例资料不全者)分为正常体质量组(n=1 751)与超重及肥胖组(n=2 026)。记录并比较各组患者高血压、冠心病家族史、心功能不全、脑卒中病史、早发冠心病等发生情况。采用Logistic多因素回归分析法分析女性早发冠心病的独立危险因素。结果超重及肥胖组早发冠心病比例为48.0%(973/2 026),高于正常体质量组的39.9%(698/1 751),两组比较,差异有统计学意义(P<0.05)。吸烟组早发冠心病比例为53.1%(169/318),高于非吸烟组的43.5%(1 504/3 461),两组比较,差异有统计学意义(P<0.05)。吸烟、超重及肥胖是女性早发冠心病的独立危险因素(P<0.05)。结论吸烟、超重及肥胖是女性早发冠心病危险因素,及早戒烟、减重有助于降低女性早发冠心病的发病率。Objective To investigate the effects of smoking,overweight and obesity on early coronary heart disease in women.Methods A retrospective study was performed on 3 779 cases of female patients with coronary heart disease who were admitted from January 2012 to March 2014.Patients were divided into the smoking group(n=318)and non-smoking group(n=3 461),according to whether they smoked.According to the patients′body mass index,the patients(excluding 2 patients with incomplete data)were divided into the normal body mass group(n=1 751)and overweight and obese group(n=2 026).The incidence of hypertension,family history of coronary heart disease,cardiac insufficiency,history of stroke and early coronary heart disease in each group were recorded and compared.Logistic multivariate regression analysis was used to analyze the independent risk factors of early-onset coronary heart disease in women.Results The proportion of premature coronary heart disease in overweight and obese group was 48.0%(973/2 026),which was higher than that in normal body mass group(39.9%,698/1 751),and the difference between the two groups was statistically significant(P<0.05).The incidence of early coronary heart disease in the smoking group was 53.1%(169/318),which was higher than that in the non-smoking group(43.5%,1 504/3 461),(P<0.05).Smoking,overweight and obesity were independent risk factors for early coronary heart disease in women(P<0.05).Conclusion Smoking,overweight and obesity are risk factors for early onset coronary heart disease in women.

关 键 词：吸烟 肥胖 女性 早发冠心病 

分 类 号：R541[医药卫生—心血管疾病]