机构地区:[1]陕西中医药大学附属医院,陕西咸阳712000 [2]陕西中医药大学第二附属医院,陕西咸阳712000 [3]陕西中医药大学,陕西咸阳712000
出 处:《现代中西医结合杂志》2019年第31期3421-3425,共5页Modern Journal of Integrated Traditional Chinese and Western Medicine
基 金:国家自然科学基金资助项目(81574006);国家科技部中医药行业专项(201507001-06);国家中医药管理局国家中医临床研究基地业务建设科研专项课题(JDZX2015279);陕西省中医药管理局中医药科研项目(15-SCJH004);陕西省重点科技创新团队项目(2013KJT-26);陕西省自然科学计划项目(2018JM7132);陕西省咸阳市科学技术研究计划项目(2017K02-76);全国名老中医药专家刘德玉传承工作室建设资助项目
摘 要:目的 观察小针刀疗法治疗早期膝骨关节炎的有效性和安全性,为小针刀在临床中的应用提供一定依据。方法 将符合纳入标准的60例早期膝骨关节炎患者采用随机数字表法分为试验组和对照组,每组30例。试验组采用小针刀疗法治疗,每周1次,连续治疗2周;对照组采用中频电疗仪治疗,每天1次,1周治疗6d,连续治疗2周。观察2组治疗前及治疗2周、1个月、2个月、3个月后疼痛VAS评分、WOMAC功能评分,比较2组治疗2周、1个月、2个月、3个月后临床疗效,记录治疗期间不良反应发生情况。结果2组治疗2周、1个月、2个月、3个月后疼痛VAS评分、WOMAC功能评分均较治疗前明显降低(P均<0.05),且试验组各时间点评分均明显低于对照组(P均<0.05);但试验组治疗3个月后及对照组治疗2个月、3个月后疼痛VAS评分及2组治疗2个月、3个月后WOMAC功能评分均较治疗2周后明显升高(P均<0.05)。试验组治疗2周、1个月、2个月、3个月后总有效率比较差异均无统计学意义(P均>0.05),但均明显高于同期对照组(P均<0.05);对照组治疗2个月、3个月后总有效率均较治疗2周、1个月后明显降低(P均<0.05)。2组治疗过程中均未出现明显不适。结论 小针刀疗法、物理疗法治疗早期膝骨关节炎都能减轻患者局部疼痛,改善患膝关节功能,但小针刀疗法治疗效果维持时间长,可延缓膝骨关节炎的进展,是一种治疗早期膝骨关节炎的安全有效方法。Objective It is to observe the effectiveness and safety of small needle knife therapy in the treatment of early knee osteoarthritis, and to provide some evidence for the application of small needle knife in clinic. Methods Sixty patients with early knee osteoarthritis who met the inclusion criteria were randomly divided into the experimental group and the control group by random number method, with 30 cases in each group. The experimental group was treated with small needle knife therapy once a week for 2 weeks. The control group was treated with medium frequency electrotherapy, once a day, 6 days in a week, and continuous treatment for 2 weeks. The pain VAS score and WOMAC function score were observed before treatment and in 2 weeks, one month, 2 months and 3 months after treatment in the two groups, the clinical curative effect were compared between the two groups after treated for 2 weeks, one month, 2 months and 3 months. The occurrence of adverse reactions during treatment was recorded in the two groups. Results The pain VAS scores and WOMAC function scores of the 2 groups after treatment for 2 weeks, one month, 2 months and 3 months were significantly lower than those before treatment(P<0.05), and the scores of the experiment group were significantly lower than those in the control group at each time(P<0.05);furthermore, the pain VAS scores of the experimental group after 3 months of treatment and the control group after 2 months and 3 months, and the WOMAC functional scores after 2 months and 3 months of treatment in the 2 groups were significantly higher than those after 2 weeks of treatment in each group(P<0.05). There was no significant difference in the total effective rate after treatment for 2 weeks, one month, 2 months and 3 months in the experiment group(P>0.05), but they were all significantly higher than those in the control group at the same time period(P<0.05). The total effective rate of the control group after treatment for 2 months and 3 months was significantly lower than that after treatme
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