1例服用甲巯咪唑致严重粒细胞减少患者的用药监护  

Pharmaceutical care for a patient with methimazole-induced severe agranulocytosis

作　　者：海文利 胡彬[1] 侯晓叶 刘苏利[1] 冯珂臻 李娜 樊婷婷[2] 吴寅 HAI Wen-li;HU Bin;HOU Xiao-ye;LIU Su-li;FENG Ke-zhen;LI Na;FAN Ting-ting;WU Yin(Pharmacy Department,Xi'an Gaoxin Hospital,Xi'an 710075;Pharmacy Department,Xijing Hospital,Xi'an 710032,China)

机构地区：[1]西安高新医院药剂科,陕西西安710075 [2]西京医院药剂科,陕西西安710032

出　　处：《临床医学研究与实践》2019年第31期11-12,15,共3页Clinical Research and Practice

摘　　要：目的探讨临床药师在药源性粒细胞缺乏症治疗中的作用。方法临床药师对1例甲巯咪唑所致严重粒细胞减少病例进行不良反应处理、抗感染药物选择、患者教育及随访,全程跟踪并进行药学监护。结果患者药源性粒细胞缺乏症伴发热最终治愈,出院后在外院顺利进行131I治疗。结论临床药师对药源性粒细胞缺乏症患者提供药学监护,充分发挥了专业特长,提高了临床治疗效果和用药安全性。Objective To explore the function of clinical pharmacists in treatment of drug-induced agranulocytosis. Methods The clinical pharmacists treated a case of severe agranulocytopenia caused by methimazole with adverse reactions, selection of anti-infective drugs, patient education and follow-up, and follow up the whole process and carry out pharmaceutical care. Results The patient with drug-induced agranulocytosis and fever induced by methimazole was cured, and underwent 131I treatment smoothly in other hospital after discharge. Conclusion The clinical pharmacists provide pharmaceutical care for patients with drug-induced agranulocytosis, giving full play to their professional expertise, which improves the clinical therapeutic effect and drug safety.

关 键 词：甲巯咪唑 粒细胞减少 药学监护 

分 类 号：R977.14[医药卫生—药品]