冠状动脉微血管功能障碍诊治的研究进展  

Diagnosis and Treatment of Coronary Microvascular Dysfunction

作　　者：何小刚 袁霄[1] 罗素新[1] HE Xiaogang;YUAN Xiao;LUO Suxin(Department of Cardiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China)

机构地区：[1]重庆医科大学附属第一医院心血管内科

出　　处：《心血管病学进展》2019年第7期988-991,共4页Advances in Cardiovascular Diseases

摘　　要：近年来,冠状动脉微血管功能障碍被认为是心绞痛的一个关键致病机制。在无动脉粥样硬化的人群中,冠状动脉微血管的功能和结构异常也可导致心肌缺血,进而诱发微血管性心绞痛。广义的微血管性心绞痛还涉及到阻塞性冠心病患者、冠状动脉血运重建术或心脏移植术后心绞痛的患者。现讨论冠状动脉微血管功能障碍在缺血性心脏病发病机制中的重要作用、微血管性心绞痛患者的临床特点和可能的诊治策略。In recent years, coronary microvascular dysfunction has been considered as an important pathogenic mechanism in angina pectoris. For people without atherosclerosis, the abnormal function and structure of coronary microvasculature can also lead to myocardial ischemia, and subsequent microvascular angina. Nevertheless, the generalized concept of microvascular angina should also refer to patients with obstructive coronary artery disease and individuals with angina after coronary revascularization or heart transplantation. This article discusses the fundamental role that coronary microvascular dysfunction plays in the pathogenesis of ischemic heart disease, the clinical characteristics of patients presenting with microvascular angina, and possible diagnostic and therapeutic strategies.

关 键 词：冠状动脉微血管功能障碍 微血管性心绞痛 诊治策略 

分 类 号：R541.4[医药卫生—心血管疾病]