六味地黄汤加减在免疫性不孕中的疗效及对相关抗体的影响研究  

Efficacy of the Liuwei Dihuang decoction on immune infertility and related antibodies

作　　者：陈秋旻 刘尊居 伍德娜[3] 陈秋月[1] Chen Qiumin

机构地区：[1]厦门大学附属第一医院杏林院区,福建厦门361022 [2]厦门市集美区灌口中心卫生院,福建厦门361023 [3]厦门大学附属第一医院,福建厦门361001

出　　处：《中医临床研究》2019年第25期61-63,共3页Clinical Journal Of Chinese Medicine

摘　　要：目的:探讨六味地黄汤加减在免疫性不孕症患者中的临床疗效及对相关抗体的影响。方法:选择我院2017 年1月- 2018 年4 月收治的84 例免疫性不孕患者,按照就诊先后顺序及自愿原则,分为对照组与观察组,每组42 例。对照组采用常规西药治疗方式,观察组采用中药汤剂六味地黄汤口服治疗,7 d 为一个治疗周期,连续治疗5 个周期。观察两组患者临床治疗效果及免疫性抗体[抗精子抗体(Antispern Antibody,AsAb)、抗卵巢抗体(Anti-ovary Antibody,AoAb)、抗子宫内膜抗体(Antiendometrial Antibody,EmAb)、抗绒毛膜促性腺激素抗体(Anti-hCG Antibody,HCGAb)]转阴率的变化。结果:①观察组与对照组的临床治疗总有效率分别为92.86%(39/42)、71.43%(30/42),差异具有统计学意义(P < 0.05);②观察组治疗后AsAb、AoAb、EmAb、HCGAb 转阴率与对照组抗体指标转阴率比较均升高,差异均有统计学意义(P < 0.05)。结论:对于免疫性不孕患者采用六味地黄汤加减治疗,与常规西药方式治疗比较,其临床治疗效果更加显著,提高了4 种抗体的转阴率,使患者更好的受孕。Objective: To investigate the clinical efficacy of the Liuwei Dihuang decoction (六味地黄汤) on immune infertility and related antibodies. Methods: 84 patients were divided into the control group and the observation group, 42 cases in each group. The patients in the control group were treated with conventional western medicine. The patients in the observation group were treated with the Liuwei Dihuang decoction. Results: The total efficiency in the observation group and the control group were 92.86% and 71.43%(P<0.05). The negative rate of AsAb, AoAb, EmAb and HCGAb in the observation group and the control group were increased after treatment (P<0.05). Conclusion: The Liuwei Dihuang decoction is more effective on immune infertility.

关 键 词：免疫性不孕 六味地黄汤 相关抗体 转阴率 

分 类 号：R274.14[医药卫生—中医骨伤科学]