高氯酸高效催化β-萘酚与醛的缩合反应  

Highly chlorinated acid catalyzes the condensation reaction of β-naphthol with aldehyde

作　　者：丁思宇 周天睿 高红 陈钢 应安国 DING Siyu;ZHOU Tianrui;GAO Hong;CHEN Gang;YING Anguo(College of Pharmaceutical,Chemical and Material Engineering,Taizhou University,Taizhou 318000,Zhejiang,China;Institute of Applied Chemistry,Taizhou University,Taizhou 318000,Zhejiang,China)

机构地区：[1]台州学院医药化工与材料工程学院,浙江台州318000 [2]台州学院应用化学研究所,浙江台州318000

出　　处：《化学研究》2019年第4期391-397,共7页Chemical Research

基　　金：国家自然科学基金项目(21576176)

摘　　要：研究了以β-萘酚和醛为原料,高氯酸为催化剂,在以1,2-二氯乙烷为溶剂的体系中,合成制备14-烷基(芳基)-14H-二苯并[a,j]氧杂蒽衍生物的方法.研究结果表明:在85℃下进行,当醛为芳香醛时,产率高达85%~96%;当醛为脂肪醛时,产率为76%~85%.因此,该方法催化时间短,反应速率快,产率高,操作简便.A series of 14-alkyl(aryl)-14H-dibenzo[a,j]xanthene derivatives were synthesized by using beta-naphthol and aldehyde as raw materials, perchloric acid as catalyst and 1,2-dichloroethane as solvent. The results showed that at 85 ℃, when the aldehyde was aromatic aldehyde, the yield was as high as 85% to 96%;while when the aldehyde was fatty aldehyde, the yield was 76% to 85%. Therefore, this method had the advantages of short catalytic time, fast reaction rate, high yield, readily work-up.

关 键 词：Β-萘酚 醛 高氯酸 氧杂蒽 

分 类 号：O626.3[理学—有机化学]