输卵管注药绝育术后盆腔X光片显影长度与绝育效果关系的生命表法分析  

Life Table Analysis on the Relation between the Contraceptive Effictiveness and the Film Length of the Occlusion for Female Tube Sterilization by Chemical Instillation.

作　　者：刘云嵘 

机构地区：[1]国家计划生育委员会科学技术研究所社会医学研究室,研究员北京100081

出　　处：《中国计划生育学杂志》2002年第11期676-678,共3页Chinese Journal of Family Planning

基　　金：国家计划生育委员会科研项目获“九五”期间国家计划生育科研成果

摘　　要：资料得自国家计划生育委员会科研项目“输卵管注药绝育术有效性安全性五年随访研究”。本文分析的特点是施该术后摄盆腔X光片测量粘堵剂充盈输卵管的显影长度,并按显影长度分组采用生命表法计算各亚组的粗累积失败率。结果显示,峡部≤1.4cm亚组和峡部≥1.5cm各亚组的粗累积失败率间差别经Log-rank检验有统计学意义(P<0.01),且粘堵剂复方苯酚糊剂(PAP)的绝育效果明显优于显影苯酚胶浆(PM)。在讨论中指出,由于PAP中含有极少量的阿的平,尽管该术在我国广泛应用中从未见到与女性生殖系统恶性肿瘤有关联的报导,但关注这一问题是极为重要的。为慎重起见,有必要在既往施该术较为普及的地区开展“病例-对照研究”以澄清或确证女性生殖系统恶性肿瘤的发生是否与实施本术后暴露于阿的平相联系,其研究结果将有助于决策。Objective:To explore the association between the cumulative failure rates and the film length of the occlusion by chemical reagents for the tubal sterilization. Methods; A multi - center randomized trial was conducted and a multiple decrement life table method was used. Results: At the 60th ordinal month,there was a high significant difference in the gross cumulative failure rates between the film length ≤ 1. 4cm group and 1.5 - 1. 9cm group (P < 0. 01) , regardless of any side of the fallopian tube instilled by chemicals for PAP and PM. At any ordinal month,the gross cumulative failure rates for PAP were lower than that for PM. Conclusion;The determinable factor was the standard for instilling chemicals when the length in both tubes were≥1. 5cm. The efficacy of PAP was significantly higher than that of PM.

关 键 词：输卵管注药绝育术 盆腔X光摄影术 生命表法 节育效果 

分 类 号：R713.5[医药卫生—妇产科学]