车间环境诱变剂的紫露草微核原位监测的应用研究  

APPLIED RESEARCH ON TRADESCANTIA MICRONUCLEUS (TRADMCN) FOR IN SITU MONITORING OF ENVIRONMENTAL MUTAGENS IN WORKSHOPS

作　　者：李来玉[1] 陈润涛[1] 梁丽燕[1] 陈锐锋[1] 

机构地区：[1]广东省职业病防治院毒理研究室,广州510260

出　　处：《癌变．畸变．突变》1992年第6期38-41,31,共5页Carcinogenesis,Teratogenesis & Mutagenesis

摘　　要：对炼油及化工等6家工厂的22个工种进行了为期两年的紫露草微核原位监测以及车间环境中毒物测定。12个工种的环境中有诱变剂或潜在致癌物,其中空气毒物浓度超过MAC的5个工种紫露草监测呈阳性,而毒物未超过MAC的7个工种均为阴性。另10个工种未接触诱变剂。其中的5个工种环境空气毒物浓度虽超过MAC,但紫露草微核原位监测全部阴性。结果表明,在生产环境诱变剂的监测上,紫露草微核原位监测有一定的敏感性,特异性和可行性。By using Trad-MCN system, in situ monitoring of environmental mutagens were carried out on 22 different types of workshops in 6 oil refineries and chemical plants during the past two years. And the concentrations of toxic substances in the workshops were also determined. Among the 22 types of work shops, 12 were polluted with mutagens or potential carcinogens, 5 of which with the concentrations of gaseous toxicants higher than the MAC showed positive results in Trad-MCN test, the other 7 with the toxic levels under the MAC showed negative effects on Trad-MCN. The rest 10 workshops did not expose to mutagens and all results of Trad-MCN were negative although 5 of them were in the concentrations of gaseous toxicants higher than the MAC. The study suggested that the Trad-MCN in situ monitering of environmental mutagens in workshops can be a specific, sensitive and practiable indicator.

关 键 词：诱变剂 车间环境 紫露草 微核 

分 类 号：R994.6[医药卫生—毒理学]