用尿谷胱甘肽过氧化物酶评定颈椎病的康复疗效  

Evaluate the Rehabilitative Effect of Cervical Spondylosis by Assaying Urinary Glutathione Peroxidase

作　　者：王玉龙[1] 吴毅文[1] 王茂音[2] 方敏[2] 

机构地区：[1]安徽医科大学附属一院康复运动医学科 [2]安徽医科大学生化教研室

出　　处：《安徽医科大学学报》1992年第3期171-173,共3页Acta Universitatis Medicinalis Anhui

摘　　要：测定了44例颈椎病患者康复前后尿液中谷胱甘肤过氧化物酶(GSH-Px)活力的变化。患者在治疗前,尿中GSH-Px活力为1080±310U/L((?)±s),与健康对照组相比差异有高度显著性(P<0.001)。推拿和颈牵治疗后尿中GSH—Px活力平均下降38.8%,且下降幅度和疗效之间有着明显的平行关系。据此,我们认为颈椎病的发病可能和体内自由基代谢紊乱有关,同时认为,无创伤的尿GSH—Px活力测定可以作为颈椎病康复疗效评定的客观指标,从而为颈椎病康复疗效的评定提供科学的生化依据。The activity of glutathione peroxidase (GSH—Px) in urine of 44 cases of patients with cervical spondylosis before and after rehabilitative therapy were measured. Before treatment, the activity of GSH—Px was 1080±310U/L((?)±s), statistically significantly higher (P<0.001) than the control group After manipulation and neck-traction, the decrease amplitude of the enzyme activity was 38.8% on the average. The decrease was parallel to the curative effect. It is dedueted from the fact of the urinary GSH—Px change in cervical spondylosis suffers that the disorder might be related to free radical disease, And urinary GSH—Px assay may be used as an index of therapeutic effect.

关 键 词：尿 谷胱甘肽 过氧化酶类 颈椎病 

分 类 号：R681.550.9[医药卫生—骨科学]