胎儿睾丸移植治疗男性低睾酮血症的临床应用  

Fetal Testis Transplantation for the Treatment of Male Hypoandrogenism

作　　者：胡云飞[1] 王玲珑[1] 杨嗣星[1] 张孝斌[1] 刘修恒[1] 詹炳炎[1] 

机构地区：[1]武汉大学人民医院泌尿外科,武汉430060

出　　处：《武汉大学学报（医学版）》2002年第4期362-363,共2页Medical Journal of Wuhan University

基　　金：湖北省教育厅资助项目(SW-97A054)

摘　　要：目的:探讨胎儿睾丸移植在男性低睾酮血症治疗中的临床应用价值。方法:利用显微外科技术,以胎儿睾丸作移植体,为8例男性低睾酮血症患者施行了胎儿睾丸移植术。结果:术后5个月,8例患者的血清睾酮水平明显升高,性欲、性功能及第二性征明显改善,移植睾丸体积较术前增大。结论:胎儿睾丸移植治疗男性低睾酮血症有效,且胎儿睾丸免疫原性低,具有较高的临床应用价值。Objective: To investigate the value of the clinical application of fetal testis for the treatment of male hypogonadism. Methods: We had performed the testicular transplantation to cure 8 patients suffered from hypogonadism with the fetal testis as donor tissue. Results: All patients had a significantly increased level of serum testosterone, and the male secondary sexual characteristics and the sexual desire were improved. The size of testis was larger than that before operation. Conclusion: Fetal testis transplantation is an effective method to cure male hypogonadism and has great value of clinical application for its weak immunogenicity.

关 键 词：临床应用 睾丸 移植 低睾酮血症 治疗 

分 类 号：R697.220.5[医药卫生—泌尿科学]