彩色多普勒超声对移植肾排斥反应肾动脉血流动力学变化的研究  

Ultrasound Study on Renal Arterial Hemodynamics in the Patients with Renal Transplantation Rejection

作　　者：廖明松[1] 李树森[1] 赵金英[1] 梁燕[1] 邓旦[1] 马琳英[1] 

机构地区：[1]成都军区总医院超声科,四川成都市610083

出　　处：《中国超声医学杂志》2002年第11期837-840,共4页Chinese Journal of Ultrasound in Medicine

摘　　要：目的 :探讨移植肾排斥反应肾动脉血流动力学变化规律及临床意义。方法 :应用超声对 98例移植肾患者和 5 3例正常人的肾脏各级肾动脉血流参数进行对比研究。结果 :1肾功能稳定期 ,四级肾动脉血流参数与正常人相似 (P>0 .5 ) ;2急性排斥反应期 ,各级肾动脉收缩期峰值血流速度 (Vp)变化不大 (P>0 .0 5 ) ,而舒张期最小血流速度 (Vmin)和平均血流速度 (Vmean)减低 ,阻力指数 (RI)及脉动指数 (PI)增高 (P<0 .0 5 ) ;3慢性排斥反应期 ,主肾动脉和段动脉 Vp、 Vmin、 Vmean均减低 (P<0 .0 1) ,RI及 PI增高 (P<0 .0 5 ) ,叶间动脉舒张期血流频谱很低甚至无频谱信号 ,弓型动脉几乎没有频谱或仅见少许脉冲样频谱 ,叶间动脉和能测到的弓型动脉血流速度均降低 (P<0 .0 1) ,RI、 PI显著增高 (P<0 .0 5 ) ;4急性排斥及慢性排斥反应期 ,给予有效治疗后 ,各级肾动脉血流参数均有所改善。结论 :超声测定移植肾各级肾动脉血流参数 ,对早期诊断排斥反应很有价值 。Objective:To study renal arterial hemodynamics and its clinical significance in the patients with renal transplantation rejection.Methods:Ninety-eight renal transplant cases and 53 health persons were studied by ultrasound.Results:When the patients' renal functions were normal, their blood flow parameters of renal arteries at all levels were normal,and similar as the control( P >0 5).In case of acute rejection, from main renal arteries to arciform arteries the peak velocity(Vp) was normal( P >0 05);the minimum velocity(Vmin) and the mean velocity(Vmean)were slowed( P <0 05),and the resistance index(RI) and the pulse index(PI) were high( P <0 05).In chronic rejection cases, the blood flow velocity of renal arteries at all levels was slowed( P <0 01),the RI and PI were remarkably high( P <0 05),and the waveforms of the interlobar and arciform arteries were very low, even disappeared After effective treatment, both the acute and the chronic rejection showed the blood flow parameters of renal arteries at all levels improved to some extent.Conclusions:It is valuable to both early diagnosis and treatment of rejection to monitor the blood flow parameters of renal arteries at all levels by ultrasound.

关 键 词：彩色多普勒超声 移植肾 排斥反应 肾动脉 血流动力学 临床意义 

分 类 号：R445.1[医药卫生—影像医学与核医学] R699.2[医药卫生—诊断学]