慢性鼻窦炎患者上颌窦粘膜微循环观察  

Microcirculation evaluation of the maxillary sinus mucosa in patients with chronic sinusitis

作　　者：李延忠[1] 扬明锋 房振胜[3] 杜志华[3] 赵文波[3] 

机构地区：[1]山东大学卫生部耳鼻喉科学重点实验室,济南250012 [2]泰山医学院微循环研究所 [3]泰山医学院附属医院耳鼻咽喉科

出　　处：《临床耳鼻咽喉科杂志》2002年第11期579-580,共2页Journal of Clinical Otorhinolaryngology

基　　金：山东省卫生厅青年科学研究基金资助项目(No.1998CA2CDA1)

摘　　要：目的:探讨慢性鼻窦炎患者上颌窦粘膜微循环血流量的变化。方法:在鼻窦内窥镜引导下应用激光多普勒血流计检测10例慢性单纯性鼻窦炎患者(慢性单纯性鼻窦炎组),10例慢性鼻窦炎伴鼻息肉患者(慢性鼻窦炎伴鼻息肉组)及10例健康者(正常对照组)上颌窦粘膜微循环血流量的状况。结果:慢性单纯性鼻窦炎组和慢性鼻窦炎伴鼻息肉组上颌窦粘膜的微循环血流量均下降,分别与正常对照组相比较,其差异均有显著性意义(分别为P<0.05和P<0.01),但两组间比较,其差异无显著性意义(P>0.05)。结论:慢性鼻窦炎患者上颌窦粘膜微循环血流量明显减少。Objective: To evaluate the microcirculation change in the maxillary sinus mucosa of patients with chronic sinusitis. Method: The microcirculation blood flow in the maxillary sinus mucosa of 20 patients with chronic sinusitis and 10 healthy controls was evaluated by means of nasal endoscopy-guided laser Doppler flowmetry. Result: The microcirculation blood flow were significantly reduced in the maxillary sinus mucosa of patients with chronic sinusitis (including type 1 and type II ) compared with healthy controls( P <0. 05, P <0. 01). There were no significantly difference between the two types of chronic sinusitis. Conclusion; The microcirculation blood flow were reduced in the maxillary sinus mucosa of patients with chronic sinusitis.

关 键 词：上颌窦粘膜 慢性鼻窦炎 微循环 激光多普勒血流计 

分 类 号：R765.41[医药卫生—耳鼻咽喉科]