高原地区用Amplatzer封堵器治疗动脉导管未闭  

Transcatheter closure of patent ductus arteriosus using the Amplatzer occluder at high altitudearea

作　　者：祁国荣 杨延平 

机构地区：[1]青海省心血管病专科医院外科,西宁810012

出　　处：《临床心血管病杂志》2002年第11期551-552,共2页Journal of Clinical Cardiology

摘　　要：目的:应用Amplatzer封堵器在高原地区治疗动脉导管未闭(PDA)并评价其疗效。方法:本组40例,年龄1.5～44(22.5±14.2)岁,PDA最窄处内径5～14(9.3±3.3)mm,均用Amplatzer封堵器介入治疗。结果:19例成功,1例严重阻塞性肺动脉高压不适宜封堵。术后即刻降主动脉造影显示35例封堵完全无残余分流,4例少量残余分流。1例术后1h封堵器脱落入右肺动脉,第3小时急诊外科手术关闭PDA并取出封堵器。24 h彩色多普勒检查显示封堵36例患者均无分流,随访2个月～1年半,无一例分流。结论:高原地区PDA发病率高,并发肺动脉高压早且多,巨大PDA(内径>0.8 cm)比率高,用Amplatzer封堵器治疗PDA是高原地区一种适应性强、安全有效的介入治疗方法。Objective:To evaluate the efficiency of transcatheter closure of patent ductus areriosus (PDA) using the Amplatzer occluder device at high altitudearea. Methods; Fourty patients with PDAmedian age of (22. 5±14. 2)(range 1. 5 to 44. 0)years. The mean PDAdiameter at its narrowest segment was (9. 3±3. 3)(rang 8. 0 to 14. 0 )mm. Results:39 to 40 cases with PDA underwent successful attempted transcatheter closure with the Amplatzer occluder. One case were aborted because of the resistant pulmonary hypertension. Angiography showed that 35 patients had complete immediate closure, 4 had small shunt 10 minutes alter the procedures. The occluder dropped into the right pulmonary artery in one case , which was taken out through the emergency surgical operation and PDA was closed. The color doppler within 24 hours revested complete closure in 36 patients. No residual shunt and PDA regurgitation after the complete closure were found in 2 to 18 months following up. Conclusion:The incidence of PDA including huge PDA with the diameter>0. 8 cm, was very high at high altitude and complicated early and frequently with pulmonary hypertension. Anterograde transcatheter closure using the Amplatzer occluder device proved a safe and effective interventional therapy for PDA patients with high successful rate and immediate satisfying results.

关 键 词：高原地区 动脉导管未闭 心脏导管介入术 AMPLATZER封堵器 PDA 

分 类 号：R541.1[医药卫生—心血管疾病]