血液病患者弓形虫感染情况调查  

TOXOPLASMA INFECTION IN PATIENTS WITH BLOOD DISEASES

作　　者：向选东[1] 段少君[1] 欧阳颗[1] 

机构地区：[1]中南大学湘雅医院,长沙410008

出　　处：《中国现代医学杂志》2002年第21期55-56,58,共3页China Journal of Modern Medicine

摘　　要：目的 :探讨血液病与弓形虫感染的关系。方法 :采用间接血凝试验 (IHA)与酶联免疫吸附试验 (ELISA)对 6 2例各种血液病患者血清中的弓形虫抗体进行检测 ,并用IHA检测对照组中 85例医院职工、118例献血员、5 8例急性感染性疾病患者及 84例慢性肝病患者血清中的弓形虫抗体。结果 :各种血液病患者IHA阳性率为 2 5 .81% ,ELISA阳性率为 2 9.0 3%。IHA检测医院职工的阳性率为 2 .35 % ,献血员为 2 .5 4 % ,急性感染性疾病为 1.72 % ,慢性肝病为 3.5 7% ,均明显低于血液病患者的阳性率。结论 :血液病患者容易并发弓形虫感染 ,临床上应对此引起高度重视。Objective:To explore the relationship between blood diseases and Toxoplasma infection.Method:Both indirect hemagglutination assay(IHA) and enzyme-linked immunosorbent assay(ELISA) were used to detect the antibody against Toxoplasma gondii in the sera of 62 patients with blood diseases. Detection of anti-Toxoplasma antibody in the sera of 85 hospital staff members, 118 blood donors,58 cases suffering from acute infection and 84 patients with chronic hepatic diseases was carried out as control. Result:The positive rates of IHA and ELISA in 62 patients with blood diseases were 25.81% and 29.03%. The lower positive rates were found in the control individuals while IHA was employed. They were 2.35% in the hospital staff members, 2.54% in the blood donors, 1.72% in the patients with acute infections and 3.57% in the cases of chronic hepatic diseases, respectively.Conclusion: Patients with blood diseases, in particular malignant ones, were susceptible to Toxoplasma infection. Doctors should pay much attention to this parasitic disease when treating and following up the patients with blood diseases.

关 键 词：弓形虫感染 血液病 抗体检测 间接血凝试验 酶联免疫吸附试验 合并症 

分 类 号：R531.8[医药卫生—内科学] R55[医药卫生—临床医学]