镰刀菌素对小鼠脂质过氧化的影响以及硒的保护作用  

THE EFFECTS OF MONILIFORMIN ON LIPID PEROXIDATION AND A PROTECTIVE EFFCCT OF SELENIUM IN MOUSE

作　　者：唐家骏[1] 芮海凤[1] 

机构地区：[1]中国科学院生态环境研究中心

出　　处：《环境化学》1989年第6期23-26,共4页Environmental Chemistry

摘　　要：小鼠饮用含有0.25ppm Kappa-硒化卡拉胶硒的饮水两个月,全血硒含量和GSH_(px)活性均显著提高,与对照相比,血清荧光产物降低22％,肝脏荧光产物降低5％;而饮用含有10ppm镰刀菌素饮水的小鼠血清荧光产物提高了22％,肝脏荧光产物提高了13.6％;饮水中同时含有0.25ppm Kappa-硒化卡拉胶硒和10ppm镰刀菌素时,硒完全抑制了镰刀菌素促进脂质过氧化的作用.血清荧光光谱和全血红外差光谱提供了大分子结构变化的信息.Adding Kappa-selenocarrageenan (0.25ppm Se) to drinking water to mice for two months significantly increased the concentration of selenium and the giutathionc peroxidase activity in whole blood. Compared with control tests, fluorescent product of peroxidizing lipid components in serum and liver from the mice decreased by 22% and 5 % respectively, while it increased by 20% and 13.6% respectively when the mice were given 10ppm moniliformin in drinking water.Selenium completely depressed the acceleration of lipid peroxidation by moniliformin when adding both 0.25 ppm Kappa-sclenocarrageenan selenium and 10 Ppm moniliformin in drinking water.Fluorescence absorption spectra and IR differential spectra have shown a significant signal in changes of macromoleculer structure.

关 键 词：镰刀菌素 鼠 过氧化 脂质 硒 

分 类 号：Q959.837[生物学—动物学]