版纳微型猪近交系肾脏的应用解剖研究  

EXPERIMENTAL STUDY ON KIDNEY ANATOMIC STRUCTURE OF BANNA MINIPIG INBRED-LINES FOR XENOTRANSPLANTATION

作　　者：朱楚洪[1] 糜建红[1] 应大君[1] 孙建森[1] 张伟[1] 朱星红[1] 姚远[1] 曾养志[2] 

机构地区：[1]第三军医大学解剖教研室国家教育部生物力学与组织工程重点实验室生物力学研究室,重庆400038 [2]云南农业大学

出　　处：《中国修复重建外科杂志》2002年第6期432-434,共3页Chinese Journal of Reparative and Reconstructive Surgery

基　　金：国家自然科学基金资助项目 ( 39870 393)

摘　　要：目的　了解版纳微型猪近交系肾脏的解剖结构 ,为异种肾移植提供基础资料。　方法　版纳微型猪近交系 2 0头处死后 ,解剖显微镜及游标卡尺检测新鲜及灌注固定的原位和离体肾脏、肾血管及输尿管 ,将肾脏组织标本石蜡包埋行 HE染色。　结果　猪肾脏组织、出入的肾血管及输尿管类似人的相应结构 ,猪肾脏皮质厚度为 (2 0 .0±2 .4) mm,肾动脉平均直径与人髂内动脉直径平均值 5.1 mm相接近 ,所有被测肾均为单支动脉。肾被膜与人肾相似 ,均为纤维层、脂肪层及肾筋膜。左右输尿管直径分别为 5.1 mm和 4.7mm。Objective To explore the kidney anatomic structure of banna minipig inbred lines, and to provide data for kidney xenotransplantation. Methods The fresh and infused kidneys of banna minipig (including the vessel and the ureter) were checked by anatomic microscope and vernier caliper in original location and away body. The tissue structure was observed by HE stain. Results The structure of kidney of banna minipig inbred lines (including the vessel and the ureter) are similar to that of human being. The fascia propria of kidney is divided into three layers including capsula fibrosa, capsula adipose and fascia renalis. The thickness of cortex renalis is (20.0 ±2.4)mm. The average diameter of renal artery is 5.1 mm and is similar to that of human being. All the kidneys of banna minipig inbred lines have a single branch renal artery. The diameters of left and right ureters are 5.1 mm and 4.7 mm, respectively. Conclusion The kidney of banna minipig inbred lines is an ideal replacement of human kidney for xenotransplantation.

关 键 词：异种移植 版纳微型猪近交系 肾脏 应用解剖 

分 类 号：R699.2[医药卫生—泌尿科学] R322.61[医药卫生—外科学]